1st Edition

Principles of Medical Statistics

By Alvan R. Feinstein Copyright 2002
    712 Pages 150 B/W Illustrations
    by CRC Press

    712 Pages 150 B/W Illustrations
    by Chapman & Hall

    The get-it-over-with-quickly approach to statistics has been encouraged - and often necessitated - by the short time allotted to it in most curriculums. If included at all, statistics is presented briefly, as a task to be endured mainly because pertinent questions may appear in subsequent examinations for licensure or other certifications. However, in later professional activities, clinicians and biomedical researchers will constantly be confronted with reports containing statistical expressions and analyses.

    Not just a set of cookbook recipes, Principles of Medical Statistics is designed to get you thinking about data and statistical procedures. It covers many new statistical methods and approaches like box plots, stem and leaf plots, concepts of stability, the bootstrap, and the jackknife methods of resampling. The book is arranged in a logical sequence that advances from simple to more elaborate results. The text describes all the conventional statistical procedures, and offers reasonably rigorous accounts of many of their mathematical justifications. Although the conventional mathematical principles are given a respectful account, the book provides a distinctly clinical orientation with examples and teaching exercises drawn from real world medical phenomena.

    Statistical procedures are an integral part of the basic background needed by biomedical researchers, students, and clinicians. Containing much more than most elementary texts, Principles of Medical Statistics fills the gap often found in the current curriculum. It repairs the imbalance that gives so little attention to the role of statistics as a prime component of basic biomedical education.

    Introduction. Formation and Expression of Data. EVALUATING A SINGLE GROUP OF DATA. Central Index of a Group. Indexes of Inner Location. Inner Zones and Spreads. Probabilities and Standardized Indexes. Stability and Confidence Intervals: Means and Medians. Stability and Confidence Intervals: Binary Proportions. Communication and Display of Univariate Data. COMPARING TWO GROUPS OF DATA. Quantitative Contrasts: The Magnitude of Distinctions. Testing Stochastic Hypotheses. Permutation Procedures: Fisher Exact and Pitman-Welch Tests. Parametric Contrasts: Z and t Tests. Chi-Square Test and Evaluation of Two Proportions. Non-Parametric Rank Tests. Displays and Interpretations for Two-Group Contrasts . Special Arrangements for Rates and Proportions. EVALUATING ASSOCIATIONS. Principles of Associations. Evaluating Trends. Evaluating Concordances. Conformity and Marker Tests. Survival and Longitudinal Analyses. ADDITIONAL ACTIVITIES. Alternative Hypotheses and Statistical 'Power'. Testing for 'Equivalence'. Multiple Stochastic Testing. Stratifications, Matchings, and Other "Adjustments." Indexes of Categorical Association. Non-Targeted Analyses. Analysis of Variance. REFERENCES. INDEX. ANSWERS TO EXERCISES.


    Alvan R. Feinstein