2nd Edition
Principles of Mucosal Immunology
Preface
Contributors
PART I. DEVELOPMENT AND STRUCTURE OF MUCOSAL TISSUE
1. Overview of the mucosal immune system structure
Reinhard Pabst and Per Brandtzaeg
2. Phylogeny of the mucosal immune system
Robert D. Miller and Irene Salinas
3. Immunologic and functional differences among individual compartments of the mucosal immune system
Hiroshi Kiyono, Kohtaro Fujihashi, and Jiri Mestecky
4. Secreted effectors of the innate mucosal barrier
Michael A. McGuckin, Andre J. Ouellette, and Gary D. Wu
PART II. CELLULAR CONSTITUENTS OF MUCOSAL IMMUNE SYSTEMS AND THEIR FUNCTION IN MUCOSAL HOMEOSTASIS
5. Immune function of epithelial cells
Richard S. Blumberg, Wayne Lencer, Arthur Kaser, and Jerrold R. Turner
6. Intraepithelial T cells: Specialized T cells at epithelial surfaces
Hilde Cheroutre
7. T lymphocyte populations within the lamina propria
Thomas T. MacDonald and Antonio Di Sabatino
8. Innate lymphoid cells
Gerard Eberl and Nicholas Powell
9. Role of regulatory T cells in mucosal immunity
Kenya Honda and Shohei Hori
10. Mucosal B cells and their function
Jo Spencer, Edward N. Janoff, and Per Brandtzaeg
11. Secretory immunoglobulins and their transport
Charlotte S. Kaetzel, Jiri Mestecky, and Jenny M. Woof
12. Role of dendritic cells in integrating immune responses to luminal antigens
Brian L. Kelsall and Maria Rescigno
13. Intestinal macrophages in defense of the mucosa
Lesley E. Smythies and Phillip D. Smith
14. Mucosal basophils, eosinophils, and mast cells
Edda Fiebiger and Stephan C. Bischoff
15. M cells and the follicle-associated epithelium
Hiroshi Ohno, Marian Neutra, and Ifor R. Williams
16. Lymphocyte trafficking from inductive sites to effector sites
Valerie Verhasselt, William Agace, Oliver Pabst, and Andrew Stagg
17. Mucosal tolerance
Charles O. Elson and Oliver Pabst
PART III. MICROBIAL COMMENSALISM
18. Recognition of microbe-associated molecular patterns by pattern recognition receptors
Elke Cario
19. Commensal microbiota and its relationship to homeostasis and disease
Jonathan Braun, Elaine Y. Hsiao, and Nicholas Powell
PART IV. GENITOURINARY TRACT
20. The immune system of the genitourinary tract
David A. MacIntyre and Kenneth W. Beagley
21. Mucosal immune responses to microbes in genital tract
Akiko Iwasaki
PART V. NOSE, AIRWAYS, ORAL CAVITY, AND EYES
22. Nasopharyngeal and oral immune system
Hiroshi Kiyono and Kohtaro Fujihashi
23. Bronchus-associated lymphoid tissue and immune-mediated respiratory diseases
Dale T. Umetsu and Bart Lambrecht
24. Ocular surface as mucosal immune site
Rachel R. Caspi and Anthony St. Leger
PART VI. INFECTIOUS DISEASES OF MUCOSAL SURFACES
25. Mucosal interactions with enteropathogenic bacteria
Nadine Cerf-Bensussan, Pamela Schnupf, Valérie Gaboriau-Routhiau, and Philippe J. Sansonetti
26. Helicobacter pylori infection
Diane Bimczok, Anne Müller, and Phillip D. Smith
27. Mucosal responses to helminth infections
William Gause and Richard Grencis
28. Viral infections
Sarah Elizabeth Blutt, Mary K. Estes, Satya Dandekar, and Phillip D. Smith
29. Infection-driven periodontal disease
Thomas E. Van Dyke and Mike Curtis
30. Mucosal vaccine strategies
Nils Lycke, Jan Holmgren, and Harry B. Greenberg
PART VII. SPECIFIC IMMUNE-MEDIATED DISEASES OF MUCOSAL SURFACES
31. Celiac disease
Bana Jabri and Ludvig M. Sollid
32. IgA nephropathy
Jan Novak, Bruce A. Julian, and Jiri Mestecky
33. Mucosal manifestations of immunodeficiencies
Scott Snapper, Jodie Ouahed, and Luigi D. Notarangelo
34. Inflammatory bowel disease
Giovanni Monteleone, Markus F. Neurath, and Britta Siegmund
35. Food allergies and eosinophilic gastrointestinal diseases
Cathryn Nagler and Glenn T. Furuta
Index
Biography
The Society for Mucosal Immunology advances research and education related to the field of mucosal immunology.
Phillip D. Smith, MD, is Professor of Medicine and Microbiology and The Mary J Bradford Professor of Gastroenterology, Department of Medicine at the University of Alabama at Birmingham, Alabama.
Thomas T. MacDonald, PhD, FRCPath, FMedSci, is Dean for Research and Professor of Immunology, Centre for Immunology and Infectious Disease, at Barts and the London School of Medicine and Dentistry, London.
Richard S. Blumberg, MD, is Professor of Medicine, Harvard Medical School, Chief, Gastroenterology and Hepatology Division, Brigham and Women’s Hospital, Boston, Massachusetts.
