3rd Edition

Principles of Organic Synthesis

By Richard O.C. Norman, James M. Coxon Copyright 1993
    828 Pages
    by CRC Press

    828 Pages
    by CRC Press

    This book is designed for those who have had no more than a brief introduction to organic chemistry and who require a broad understanding of the subject. The book is in two parts. In Part I, reaction mechanism is set in its wider context of the basic principles and concepts that underlie chemical reactions: chemical thermodynamics, structural theory, theories of reaction kinetics, mechanism itself and stereochemistry. In Part II these principles and concepts are applied to the formation of particular types of bonds, groupings, and compounds. The final chapter in Part II describes the planning and detailed execution of the multi-step syntheses of several complex, naturally occurring compounds.

    Chemical Thermodynamics.

    Molecular Structure.

    Chemical Kinetics.



    Formation of Carbon-carbon Bonds.

    Formation of Aliphatic Carbon-carbon Bonds.

    Pericyclic Reactions.

    Formation of Aliphatic Carbon-nitrogen Bonds.

    Electrophilic Aromatic Substitution.

    Nucleophilic Aromatic Substitution.

    Aromatic Diazonium Salts. Molecular Rearrangements.

    Reagents Containing Phosphorus, Sulfur, Silicon or Boron.

    Photochemical Reactions.

    Free-radical Reactions.

    Organotransition and Reagents.

    Oxidation. Reduction.

    The Synthesis of Five- and Six-Membered Heterocyclic Compounds.

    The Syntheses of Some Naturally Ocurring Compounds.



    Norman, Richard O.C.