4th Edition

Principles of Physiology for the Anaesthetist

By Peter Kam, Ian Power Copyright 2020
    535 Pages
    by CRC Press

    535 Pages
    by CRC Press

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    This book provides readers with an anaesthesia-focused alternative to general physiology textbooks. The new edition has been reorganised with the trainee anaesthesist in mind, into shorter bite-sized chapters ideal for exam revision.  The content includes the physiology of all major organ systems, with specific emphasis on the nervous, respiratory, and cardiovascular systems as well as special sections on pain, aging, specific environments and obesity.  Alongside the learning objectives, reflection points and a handy summary of physiological equations and tables, there is greater emphasis on clinical application in this fourth edition, with applied physiology included in almost every section.

    Preface to the first edition

    Preface to the second edition

    Preface to the third edition

    Preface to fourth edition




    Section One: Basic Cell Physiology

    1. Cell Components and Function

    2. Physiology of Excitable Cells

    3. Neurotransmitters and Receptors, Ion Channels, G Proteins and Second Messengers

    Section Two: Physiology of the Nervous System

    4. Neuronal Function

    5. Blood–Brain Barrier and Cerebrospinal Fluid (CSF)

    6. Cerebral Circulation

    7. Spinal Cord: Anatomical and Physiological Features

    8. Sensory System

    9. Motor Function and Control: Descending Tracts

    10. Autonomic Nervous System

    11. Consciousness, EEG, Sleep and Emotions

    Section Three: Muscle Physiology

    12. Striated Muscles: Skeletal and Cardiac Muscles

    13. Muscle Spindles, Golgi Tendon Organs and Spinal Reflexes

    14. Smooth Muscle

    Section Four: Respiratory Physiology

    15. Functions of the Respiratory System

    16. Mechanical Properties of the Lungs

    17. Gas Exchange in the Lungs

    18. Carriage of Oxygen in Blood

    19. Carbon Dioxide Carriage in Blood

    20. Pulmonary Circulation

    21. Control of Ventilation

    22. Applied Respiratory Physiology

    Section Five: Cardiovascular Physiology

    23. Functions of the Cardiovascular System

    24. Electrical Properties of the Heart

    25. Mechanical Events of the Cardiac Cycle

    26. Pressure–Volume Loop of the Left Ventricle

    27. Physical Factors Governing Blood Flow Through Vessels

    28. The Systemic Circulation

    29. Microcirculation

    30. Venous Return and Vascular Function

    31. Regulation of Arterial Blood Pressure

    32. Integrated Cardiovascular Responses

    Section Six: Gastrointestinal Physiology

    33. Saliva, Swallowing, and Lower Oesophageal Sphincter

    34. Stomach: Gastric Secretions, Motility, Digestion and Vomiting

    35. The Small Intestine: Secretions, Digestion and Motility

    36. The Large Intestine

    Section Seven: Liver Physiology

    37. Functions of the Liver

    38. Liver Blood Flow

    39. Liver Function Tests and Physiological Features of Liver Failure

    Section Eight: Renal Physiology

    40. Functions of the Kidneys and Functional Anatomy

    41. Renal Blood Flow

    42. Glomerular Filtration

    43. Tubular Function

    44. The Loop of Henle and Production of Concentrated Urine: Counter-Current Mechanisms of the Kidney

    45. Overview of Renal Control of Acid–Base Balance

    46. Applied Physiology: Renal Failure

    Section Nine: Acid–Base Physiology

    47. Basic Concepts of Acid–Base Physiology

    48. Compensatory Mechanisms in Acid–Base Disorders

    49. Clinical Aspects of Acid–Base Control

    50. Anion Gap and Stewart’s Strong Ion Difference

    Section Ten: Physiology of Blood

    51. Cellular Components of Blood

    52. Plasma: The Non-Cellular Components of Blood

    53. Haemostasis

    54. Blood Transfusion

    Section Eleven: Physiology of the Immune System

    55. Immune System and Innate Immunity

    56. Acquired Immunity

    57. Cytokines

    58. Hypersensitivity

    Section Twelve: Endocrine Physiology

    59. General Aspects of Endocrine Physiology

    60. Pituitary Gland

    61. Hormones of the Pancreas

    62. Thyroid Hormones and Calcium Metabolism

    63. Hormones of the Adrenal Gland

    64. Erythropoietin, Atrial Natriuretic Peptide and Sex Hormones

    Section Thirteen: Metabolism, Nutrition, Exercise and Temperature Regulation

    65. Metabolism

    66. Nutrition

    67. Exercise Physiology

    68. Temperature Regulation

    Section Fourteen: Physiology of Pain

    69. Peripheral Mechanisms of Pain

    70. Central Modulation of Pain

    71. Pain Sensitization

    Section Fifteen: Physiology of Pregnancy, Placenta, Neonate, Ageing and Obesity

    72. Physiology of Pregnancy

    73. Physiology of the Placenta

    74. Physiology of the Neonate

    75. Physiology of Ageing

    76. Physiology of Obesity

    Section Sixteen: Special Environments

    77. Physiology Related to Special Environments

    Further reading





    Nuffield Professor of Anaesthetics, Sydney Medical School, University of Sydney
    Royal Prince Alfred Hospital
    Camperdown, Australia


    Emeritus Professor at the University of Edinburgh, Edinburgh, United Kingdom