190 Pages
by
CRC Press
190 Pages
10 Color & 24 B/W Illustrations
by
CRC Press
190 Pages
by
CRC Press
Also available as eBook on:
Prion-related diseases, known as transmissible spongiform encephalopathies (TSEs), are infectious, fatal neurodegenerative disorders for which there is no cure, treatment, nor even a means for early diagnosis. The horrific advent of Mad Cow Disease -- transmitted to humans through eating meat from steers sickened by bovine spongiform encephalopathy --brought prion-related diseases international... Read more
Prologue. Prion Diseases: Clinical Symptoms, Epidemiology and Neuropathology. The Infectious Agent and the Prion Hypothesis. The Prion Protein: Cell Biology, Genetic and Putative Function. Prion Replication by Transmission of Protein Conformation. Prion Strains and Multiple Conformations of the Prion Protein. Prions: From the Mouth to the Brain. Neurodegeneration in Prion Disease. The Diagnosis Problem and Current Tests. Therapeutic Approaches. Cyclic Amplification of Prion Protein: Rationale, Application and Perspectives. Other Diseases of Protein Misfolding. Prions: A Common Phenomenon in Biology?
Biography
Soto, Claudio
