1st Edition

Proteoglycans Structure, Biology And Molecular Interactions

Edited By Renato V. Iozzo Copyright 2000

    This book provides a comprehensive, up-to-date review of the structure, biology, and molecular interactions of proteoglycans, consolidating into a single source research using molecular, cellular, and animal systems. Of particular note is an in-depth look at the role of heparan sulfate in modulating growth factors and morphogens.

    1. Introductory Remarks and Overview 2. Structure and Biosynthesis of Chondroitin Sulfate and Hyaluronan 3. Heparan Sulfate: Molecular Structure and Interactions with Growth Factors and Morphogens 4. Hyaluronan 5. Catabolism of Proteoglycans 6. Syndecans 7. Signaling Through the Syndecan Proteoglycans 8. Glypicans 9. Serglycin Proteoglycans: The Family of Proteoglycans Stored in the Secretory Granules of Certain Effector Cells of the Immune System 10. Small Leucine-Rich Proteoglycans 11. Corneal Proteoglycans 12. Heparan Sulfate Proteoglycans in Basement Membranes: Perlecan, Agrin, and Collagen XVIII 13. Versican 14. Aggrecan 15. Chrondroitin Sulfate Proteoglycans in the Nervous System


    Iozzo\, Renato V.