Psychoneuroimmunology, Stress, and Infection: 1st Edition (Hardback) book cover

Psychoneuroimmunology, Stress, and Infection

1st Edition

By Herman Friedman, Thomas W. Klein, Andrea L. Friedman

CRC Press

304 pages

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Hardback: 9780849376382
pub: 1995-10-20
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Psychoneuroimmunology is the emerging science devoted to studying the two-way relationship between the nervous and immune systems. Psychoneuroimmunology, Stress, and Infection highlights the latest information concerning microbial infections in both man and animals as related to stress and especially stress hormones.

The volume focuses on psychoneuroimmunology as it impacts the immune system in general and also the relationship between neurological events which influence susceptibility and/or resistance to infectious agents such as bacteria, fungi and viruses, as well as parasites. Prominent researchers describe the involvement of the hypothalamus-pituitary-adrenal (HPA) axis on immunity as a function of the nervous system. The text discusses hormones such as prolactin and growth hormone and steroid induced susceptibility to infection and neuropeptides, including vasoactive intestinal peptide, and substance P. The effects of catacholamines on immunity and susceptibility to infection are also covered. This reference also details the involvement of immune cells in the synthesis of neuropeptides, including hormones and endorphins, their effect on the brain as well as the effects of interleukins and tumor necrosis factor on the central nervous system. The book concludes with an interesting look at the relationship between aging, psychoneuroimmunology, and infection.

Although there is much new knowledge concerning the nature and mechanism of immune responses, including the mediators involved, Psychoneuroimmunology, Stress, and Infection also presents important discussions and reviews that are long overdue and provide a major contribution to the area of biomedical knowledge in general and psychoneuroimmunology in particular.


"The editors and contributors create a compelling appeal for an integrated approach to the study of PNI that asks the questions to expose the nature and wonder of the biopsychosocial human being."

-Oncology Nursing Forum

Table of Contents

Brain and Immune Interactions-Historical Perspectives of Psychoneuroimmunology, R. Ader

The Central Nervous System, Hormones, and Immune Responses, A. Dunn

Neuropeptide Hormones and Receptors in the Immune Response and Infectious Diseases, J.E. Blalock

The Pituitary Gland, Psychoneuroimmunology, and Infectious Diseases, I. Berczi and A. Szentivanyi

Neurohormones, Psychoneuroimmunology, and the Immune Networks, J.J.M. Maestroni

Stress, Infections, and Psychoneuroimmunology, R. Herberman

Psychoneuroimmunology, Stress, and Disease, M. Schlesinger

Aging, Psychoneuroimmunology, and Infection, R.M. Gorczynski

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Immunology
MEDICAL / Psychiatry / General
SCIENCE / Life Sciences / Neuroscience