1st Edition

RNAi Technology





ISBN 9781578087167
Published April 28, 2011 by CRC Press
392 Pages 19 Color & 11 B/W Illustrations

USD $230.00

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Book Description

RNAi technology are used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. This book reviews the selective and robust effect of RNAi on gene expression which makes it a valuable research tool, both in cell culture and in living organisms because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. This book will introduce new technology in the study of RNA interference in microorganisms, plants and animals.

Table of Contents

Acute RNA Interference for Basic Research and Therapy, Federico Calegari
Deciphering post-transcriptional Gene Silencing Pathways Through Genetic Screens, Vincent Jauvion, Allison C. Mallory and Hervé Vaucheret
Implications of miRNA-directed Gene Silencing in Cancer, Duncan Ayers
MicroRNA Interference: Concept and Technologies, Zhiguo Wang and Xiaobin Luo
Silencing the Disease Messengers: Progress and Prospects in Developing Nucleic Acid based Therapeutics, R.H. Das and N. Verma
Artificial MicroRNA: A Third Generation RNAi Technology, P. Yadava
Pectin Methylesterase Enhances Tomato Bushy Stunt Virus P19 RNA Silencing Suppressor Effects, Tatiana V. Komarova, Vitaly Citovsky and Yuri L. Dorokhov
MicroRNAs: A New Paradigm For Gene Regulation, Luciana dos Reis Vasques, Cláudia Gasque Schoof and Eder Leite da Silva Botelho
A RNAi-based Genome-wide Screen to Discover Genes Involved in Resistance to Tomato Yellow Leaf Curl Virus (TYLCV) in Tomato, Henryk Czosnek, Dagan Sade, Rena Gorovits, Favi Vidavski, Hila Beeri, Iris Sobol and Assaf Eybishtz
RNAi for Crop Improvement, I. Amin, Md. Saeed, S. Mansoor and Rob W. Briddon
RNA Silencing and Viral Encoded Silencing Suppressors, Masato Ikegami, Tatsuya Kon and P. Sharma
Gene Silencing and Its Applications in Plants, S. Abdolhamid Angaj and Somayeh Darvishani
Use of RNAi Technology for Control of Rice Viruses, I. Dasgupta
Use of RNAi Technology in Medicinal Plants, P. Alam, A. Ali, M.A. Khan and M.Z. Abdin
RNA Interference and Wheat Functional Genomics, Pradeep Sharma
Biogenesis, Processing and Function of miRNA in Plants and Animals, S. Issar and R.K. Gaur
RNA Interference in Fungi: B.M. Bashyal and R. Aggarwal
Virulence of Fusarium spp. Causing Wilt Disease of Guava with Special Reference to RNAi, V.K. Gupta,P.K. Jain, A. Manimaran, K.M. Turner, A. O’Donovan and M. Tuohy
RNA Interference—Interactomics and Therapeutics, S. Ganguli and A. Datta
Acute RNA Interference for Basic Research and Therapy, Federico Calegari
Deciphering post-transcriptional Gene Silencing Pathways Through Genetic Screens, Vincent Jauvion, Allison C. Mallory and Hervé Vaucheret
Implications of miRNA-directed Gene Silencing in Cancer, Duncan Ayers
MicroRNA Interference: Concept and Technologies, Zhiguo Wang and Xiaobin Luo
Silencing the Disease Messengers: Progress and Prospects in Developing Nucleic Acid based Therapeutics, R.H. Das and N. Verma
Artificial MicroRNA: A Third Generation RNAi Technology, P. Yadava
Pectin Methylesterase Enhances Tomato Bushy Stunt Virus P19 RNA Silencing Suppressor Effects, Tatiana V. Komarova, Vitaly Citovsky and Yuri L. Dorokhov
MicroRNAs: A New Paradigm For Gene Regulation, Luciana dos Reis Vasques, Cláudia Gasque Schoof and Eder Leite da Silva Botelho
A RNAi-based Genome-wide Screen to Discover Genes Involved in Resistance to Tomato Yellow Leaf Curl Virus (TYLCV) in Tomato, Henryk Czosnek, Dagan Sade, Rena Gorovits, Favi Vidavski, Hila Beeri, Iris Sobol and Assaf Eybishtz
RNAi for Crop Improvement, I. Amin, Md. Saeed, S. Mansoor and Rob W. Briddon
RNA Silencing and Viral Encoded Silencing Suppressors, Masato Ikegami, Tatsuya Kon and P. Sharma
Gene Silencing and Its Applications in Plants, S. Abdolhamid Angaj and Somayeh Darvishani
Use of RNAi Technology for Control of Rice, VirusesI. Dasgupta
Use of RNAi Technology in Medicinal Plants, P. Alam, A. Ali, M.A. Khan and M.Z. Abdin
RNA Interference and Wheat Functional Genomics, Pradeep Sharma
Biogenesis, Processing and Function of miRNA in Plants and Animals, S. Issar and R.K. Gaur
RNA Interference in Fungi B.M. Bashyal and R. Aggarwal
Virulence of Fusarium spp. Causing Wilt Disease of Guava with Special Reference to RNAi, V . K .Gupta, P.K. Jain, A. Manimaran, K.M. Turner, A. O’Donovan and M. Tuohy
RNA Interference—Interactomics and Therapeutics, S. Ganguli and A. Datta

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