Radiopharmaceuticals: Chemistry and Pharmacology, 1st Edition (Hardback) book cover

Radiopharmaceuticals

Chemistry and Pharmacology, 1st Edition

Edited by Adrain D. Nunn

CRC Press

460 pages

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Hardback: 9780824786243
pub: 1992-06-19
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pub: 2018-04-27
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Description

This timely resource compares single-photon emission tomography (SPECT), used mainly withTechnetium and iodine for routine clinical examinations, and positron emission tomography(PET) , employing short-lived radionuclides of carbon, oxygen, nitrogen, and fluorine in researchinvestigations.Presenting the logic behind why one approach is better than another in various circumstances,Radio pharmaceuticals details the use of radiolabelled substrates in measuring the effect of diseaseand drugs on regional metabolism and receptor concentration/occupancy .. . discusses factorsaffecting the selective retention of small metal complexes by various tissues .. . analyzes the interactionof small exogenous metal complexes with enzymes in vivo and the critical role of stereochemistry. . . explores the use of radio labelled compounds in the study of neuroactive compounds,neurotransmitters, enzyme inhibitors, and substrates in vivo .. . covers the design and pharmacologyof radiolabelled drugs as probes of site of action , selectivity and specificity, and pharmacokineticsin vivo .. . and more.Extensively referenced with over l 050 bibliographic citations, Radiopharmaceuticals is a state-ofthe-art guide for pharmacists; organic, medicinal , and radiopharmaceutical chemists; pharmacokineticists;nuclear medicine physicians and technologists; neurochemists; and governmentregulatory personnel .

About the Series

Drugs and the Pharmaceutical Sciences

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Subject Categories

BISAC Subject Codes/Headings:
SCI013000
SCIENCE / Chemistry / General