1st Edition

Radiotherapy and Clinical Radiobiology of Head and Neck Cancer

220 Pages
by CRC Press

220 Pages 10 Color & 9 B/W Illustrations
by CRC Press

220 Pages 10 Color & 9 B/W Illustrations
by CRC Press

Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have... Read more



Preface. Introduction. Chapter 1. Introductory aspects of head and neck cancers. Chapter 2. Clinical aspects of head and neck cancer. Chapter 3. General radiobiology refresher. Chapter 4. Hypoxia and angiogenesis. Chapter 5. The mechanisms behind tumour repopulation. Chapter 6. The radiobiology of HPV-associated head and neck cancer. Chapter 7. Normal tissue tolerance. Chapter 8. The treatment of head and neck cancer. Chapter 9. Targeted therapies. Chapter 10. Retreatment issues. Appendix: Radiobiological modelling.

Biography

Loredana Marcu is Professor of Medical Physics at the University of Oradea, Romania, and Adjunct Professor at School of Health Sciences, University of South Australia. 



Iuliana Toma-Dasu is Associate Professor in Medical Radiation Physics in the Department of Physics, Stockholm University, and she is the research group leader of the Stockholm University Medical Radiation Physics division, which is affiliated with the Department of Oncology and Pathology at the Karolinska Institutet.



Alexandru Dasu is the Chief Medical Physicist at the Skandion Clinic, the national Swedish proton centre in Uppsala and Associate Professor in Medical Radiation Physics.



Claes Mercke is Professor of Radiation Oncology and one of the senior physicians at the Karolinska University Hospital, Department of Oncology, in Stockholm, Sweden.