1st Edition

Randomised Response-Adaptive Designs in Clinical Trials

By Anthony C Atkinson, Atanu Biswas Copyright 2014
340 Pages
by Chapman & Hall

340 Pages
by Chapman & Hall

339 Pages
by Chapman & Hall

Randomised Response-Adaptive Designs in Clinical Trials presents methods for the randomised allocation of treatments to patients in sequential clinical trials. Emphasizing the practical application of clinical trial designs, the book is designed for medical and applied statisticians, clinicians, and statisticians in training. After introducing clinical trials in drug development, the... Read more

Introduction: Stories and Data. Adaptive Design: Controversies and Progress. Randomised Balanced Sequential Treatment Allocation. Response-Adaptive Designs for Binary Responses. Response-Adaptive Designs for Continuous Responses. Response-Adaptive Designs for Longitudinal Responses. Optimum Biased-Coin Designs with Covariates. Optimum Response-Adaptive Designs with Covariates. Optimal Response-Adaptive Designs with Constraints. Adaptive Design: Further Important Issues. Appendix. Bibliography. Index.

Biography

Anthony C. Atkinson is an Emeritus Professor of Statistics at the London School of Economics and Political Science.



Atanu Biswas is a professor in the Applied Statistics Unit at the Indian Statistical Institute, Kolkata.