350 Pages 16 Color & 161 B/W Illustrations
by CRC Press

350 Pages 16 Color & 161 B/W Illustrations
by CRC Press

Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these... Read more

Chapter 1: Recent Advancements in New Drug Design and Development of Prodrugs

Kamal Shah, Gourav Krishna, Jeetendra Kumar Gupta, Durgesh Nandini Chauhan, Nagendra Singh Chauhan, and Pradeep Mishra

Chapter 2: Codrugs: Optimum Use through Prodrugs

Suneela Dhaneshwar, Poorva shree Joshi, and Shubham Pawar

Chapter 3: Role of Prodrugs in Drug Design

Asadullah Madni, Sobia Noreen, Afifa Shafique, Abdur Rahim, Muhammad Sarfraz, and

Attia Afzal 

Chapter 4: Prodrugs for Enhancement of Lipophilicity

Suneela Dhaneshwar and Neha Bhilare

Chapter 5: Lipidic Prodrugs for Drug Delivery: Opportunities and Challenges

Milica Markovic, Shimon Ben-Shabat, and Arik Dahan

Chapter 6: The Progress of Prodrugs in Drug Solubility

Guilherme Felipe dos Santos Fernandes, Igor Muccilo Prokopczyk, Chung Man Chin, and Jean Leandro dos Santos

Chapter 7: Prodrugs for CNS Drug Delivery

Katalin Prokai-Tatrai

Chapter 8: Prodrugs for Cancer Treatment

W.L. Stone, V. Palau and K. Krishnan

Chapter 9: Prodrugs in Cancer Nanomedicine and Therapy

Vikas Pandey, Tanweer Haider, Vishal Gour, Vandana Soni, and Prem N Gupta

Chapter 10: Nitroreductases in Prodrug Therapies

Tuğba Güngör, Ferah Cömert Önder, and Mehmet Ay  

Chapter 11: Prodrug Approach Using Carboxylesterase: Different Substrate Specificities of Human Carboxylesterase Isozymes

M. Takahashi and M. Hosokawa

Chapter 12: Mathematical Models for ADME of Prodrugs

Vipin Bhati, Navyashree V, Shamsher Singh, Pooja Chawla, and Anoop Kumar

Chapter 13: Prodrug Approaches for Natural Products

Sudhir Kumar Thukral, Pooja Chawla, Alok Sharma, and Viney Chawla

Chapter 14: Biotechnology-Based Prodrug Approach for Cell-Specific Targeting: Its Theoretical Basis and Application

Sunita Minz, Manju Rawat Singh, Deependra Singh, Arun Singh Parihar, and Madhulika Pradhan

Biography

Kamal Shah, Durgesh Nandini Chauhan, Nagendra Singh Chauhan, Pradeep Mishra