1st Edition

Reframing Pharma through Global Health and Social Science Evidence Ecologies

By Gregory Patrick Fagan Copyright 2026
186 Pages 20 B/W Illustrations
by CRC Press

186 Pages 20 B/W Illustrations
by CRC Press

This book explores how pharmaceutical evidence is designed, interpreted, and used, drawing on positivist, constructivist, critical realist, pragmatist, feminist, and decolonial traditions. It shows how dominant evidence paradigms often struggle to account for time, population heterogeneity, patient experience, and context across contemporary therapeutic and care settings. Rather than treating... Read more

Preface

Acknowledgments

Introduction

Chapter 1: The Biomedical Compact: Origins, Power, and Limits

Chapter 2: Reductionism and Evidence Design

Chapter 3: Global Health, Access, and Contextual Fracture

Chapter 4: Real-World Evidence: Promise, Inheritance, and Constraint

Chapter 5: Philosophical Stances in Practice

Chapter 6: Methodological Consequences of Pluralism

Chapter 7: Evidence Ecologies: A Framework for Alignment

Chapter 8: Designing for Coherence: Evidence Architecture in Practice

Chapter 9: Social and Anthropological Foundations of Situated Evidence

Conclusion: Designing Evidence for a World That Learns

Index

Biography

Gregory Patrick Fagan, PhD, is a global health researcher whose work examines how pharmaceutical evidence is produced, interpreted, and governed within real-world health systems. Drawing on sociology, medical anthropology, and applied epistemic analysis, he studies how assumptions embedded in evidence design shape regulation, access, and therapeutic uptake across diverse settings. He has held senior roles in global health and rare disease programs and works at the intersection of pharmaceutical development, humanitarian access, and health systems.