Reperfusion Therapy for Acute Myocardial Infarction  book cover
1st Edition

Reperfusion Therapy for Acute Myocardial Infarction

Edited By

Eric R. Bates

ISBN 9780849343582
Published March 20, 2008 by CRC Press
416 Pages

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Book Description

Reperfusion Therapy for Acute Myocardial Infarction provides a comprehensive review of reperfusion therapy for ST-segment elevation myocardial infarction (STEMI). Professor Eric R. Bates and his international team of contributors examine current and future reperfusion therapies for STEMI, in conjunction with the latest clinical trials and guidelines, to bring the most in-depth and thorough review of management strategies for these patients. This source addresses key developments that can reduce logistical barriers, improve times-to-treatment, and ensure that appropriate medications are administered in patient care.

Demonstrating the benefits of reperfusion therapy, this volume:

  • Examines fibrinolytic agents that can be used alone or in combination with other care regimens to improve the benefits of reperfusion therapy and reduce the risks of treatment
  • Summarizes the use of percutaneous coronary intervention (PCI) across the spectrum of reperfusion therapy
  • Helps specialists identify barriers to the early treatment of patients in various practice environments
  • Reviews the clinical relevance and implications of recent clinical trials and the integration of these findings into the current practice of acute reperfusion therapy

Table of Contents


Chapter 1. Historical Milestones, Eugene Braunwald, M.D.

Chapter 2. Pathophysiology of Myocardial Infarction, Prediman K. Shah, M.D.

Chapter 3. Successful Myocardial Reperfusion, C. Michael Gibson, M.D.

Fibrinolytic Reperfusion

Chapter 4. Infusion Fibrinolytic Therapy, Eric R. Bates, M.D.

Chapter 5. Bolus Fibrinolytic Therapy, Frans J. Van de Werf, M.D., Ph.D.

Chapter 6. Treatment Opportunities with Fibrinolytic Therapy, Paul W. Armstrong, M.D.

Catheter-based Reperfusion

Chapter 7. Primary PCI, William W. O’Neill, M.D.

Chapter 8. Rescue PCI, Anthony H. Gershlick, M.B.B.S.

Chapter 9. Facilitated PCI, E. Magnus Ohman, M.D.

Chapter 10. Primary PCI without On-site Surgery, Thomas P. Wharton, Jr. M.D.

Chapter 11. Transfer for Primary PCI, Brahmajee Nallamothu, M.D., M.P.H.

Adjunctive Therapy

Chapter 12. Antiplatelet Agents, Gilles Montalescot, M.D., Ph.D.

Chapter 13. Anticoagulant Agents, Christopher B. Granger, M.D.

Chapter 14. Myocyte Protection by Pharmacological Therapy, David P. Faxon, M.D.

Chapter 15. Myocyte Protection by Device Therapy, John G. Webb, M.D.

Challenges and Opportunities

Chapter 16. Optimal Strategies for Emergency Medical System and Emergency Department Triage, Judd E. Hollander, M.D.

Chapter 17. Management of Complications, Steven M. Hollenberg. MD

Chapter 18. Myocyte Regeneration, Stephen G. Ellis, M.D.

Chapter 19. The Future of Reperfusion Therapy, Elliott M. Antman, M.D.


ACC/AHA and ESC Guidelines, Eric R. Bates, M.D.

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ERIC R. BATES is Professor of Internal Medicine at the University of Michigan. Dr. Bates received his M.D. from the University of Michigan Medical School, Ann Arbor, and trained in internal medicine and cardiology at the University of Michigan Hospitals. His major clinical interests include acute myocardial infarction, acute coronary syndromes, and coronary artery disease. His research efforts have focused on fibrinolytic and catheter-based reperfusion therapy for acute myocardial infarction and cardiogenic shock, antiplatelet and anticoagulant therapy for coronary thrombosis, and coronary artery revascularization. Dr. Bates has served on the steering committees for several important international multicenter randomized clinical trials. He serves on the editorial boards of the American Journal of Cardiology, the European Journal of Cardiology, the Journal of the American College of Cardiology, the American Heart Journal, Catheterization and Cardiovascular Interventions, and Cardiology News. Dr. Bates is a member of the ACC/AHA writing committee to update the 1999 guidelines for acute myocardial infarction. He is also a member of the American Board of Internal Medicine Interventional Cardiology Test Committee.