This volume includes more than 40 important articles on integrity and misconduct, biomedical research, the social and disciplinary contexts of science, research in the social sciences, the social responsibility of science and scientists, and other core issues in research ethics. A new introduction by the editor places these articles in their historical and conceptual context. The volume provides a rich library of resources, ideas and challenges in the ethics of research for any scholar concerned with such issues.

    Contents: Introduction; Part I Foundations: Ethics and clinical research, Henry K Beecher; Experimentation in children: a re-examination of legal ethical principles, William J. Curran and Henry K. Beecher; Philosophical reflections on experimenting with human subjects, Hans Jonas; Clarifying the concepts of research ethics, Robert J. Levine. Part II Integrity and Misconduct: Fraud and the structure of science, William J. Broad; Misrepresentation and responsibility in medical research, Robert L. Engler, James W. Covell, Paul J. Friedman, Philip S. Kitcher and Richard M. Peters; Deception in scientific research, Patricia Woolf; Research integrity, Kenneth J. Ryan; From Baltimore to Bell Labs: reflections on 2 decades of debate about scientific misconduct, David B. Resnik; Trust and the future of research, Caroline Whitbeck; How to blow the whistle and still have a career afterwards, C.K. Gunsalus. Part III Biomedical Research: The conflict between randomized clinical trials and the therapeutic obligation, Fred Gifford; False hopes and best data: consent to research and the therapeutical misconception, Paul S. Appelbaum, Loren H. Roth, Charles W. Lidz, Paul Benson and William Winslade; Equipoise and the ethics of clinical research, Benjamin Freedman; Community equipoise and the ethics of the randomized clinical trials, Fred Gifford; Of mice but not men: problems of the randomized clinical trial, Samuel Hellman and Deborah S. Hellman; Randomized, controlled trials, observational studies, and the hierarchy of research designs, John Concato, Nirav Shah and Ralph I. Horwitz; A comparison of observational studies and randomized, controlled trials, Kjell Benson and Arthur J. Harz; Participation in biomedical research: the consent process as viewed by children, adolescents, young adults, and physicians, Elizabeth J. Susman, Lorah D. Dorn and John C. Fletcher; What makes clinical research ethical?, Ezekiel J. Emanuel, David Wendler and Christin Grady; What makes clinical research in developing countries ethical? The benchmarks of ethical research, Ezekiel J. Emanuel, David Wendler, Jack Killen and Christin Grady. Part IV Contexts of Science: The social process of science, Gerard Piel; Science as a vocation in the 1990s: the changing organizational culture of academic science, Edward J. Hackett; Fraud, ethics, and the disciplinary contexts of science and scholarship, Mary Frank Fox; Misconduct and social control in science: issues, problems, solutions, Mary Frank Fox and John M. Braxton; The role of culture in research misconduct, Mark S. Davis; Scientific societies as sentinels of responsible research conduct, Mark S. Frankel; Scientific societies and research integrity: what are they doing and how well are they doing it?, Margot Iverson, Mark S. Frankel, and Sanyin Siang. Part V Social Research: Psychology in action: some thoughts on the ethics of research: after reading Milgram's Behavioral Study of Obedience, Diana Baumrind; On the ethics of intervention in human psychological research: with special reference to the Stanford prison experiment, Philip G. Zimbardo; Learning to deceive, Thomas H. Murray; Observing abuse: professional ethics and personal morality in field research, Steven J. Taylor. Part VI Social Responsibility: The social responsibilities of scientists, Bertrand Russell; Notes of a biology-watcher: the hazards of science, Lewis Thomas; 2 aspects of scientific responsibility, John T. Edsall. Part VII Authorship and Data: Statistics and ethics in medical research, David L. DeMets; Problems in research integrity arising from misconceptions about the ownership of research, Kay L. Fields and Alan R. Price; The contributions of authors, Drummond Rennie, Annette Flanagin and Veronica York; Who did what? Authorship and contribution in 2001, Drummond Rennie; Reflections on determining authorship credit and authorship order on faculty-student collaborations, Mark A. Fine and Lawrence A. Kurdek. Part VIII Animals in Research: The rights of humans and other animals, Tom Regan; The case for the use of animals in biomedical research, Carl Cohen; Rethinking the morality of animal research, Jerrold Tannenbaum and Andrew N. Rowan; The moral status of mice, Harold A. Herzog Jr; Harry F. Harlow and animal research: reflection on the ethical paradox, John P. Gluck. Part IX Financial Conflicts of Interest: University research and the wages of commerce, Michael Davis; Understanding financial conflicts of interest, Dennis F. Thompson; Perception, reality, and the political context of conflict of interest in university-industry relationships, Mark S. Frankel; Is academic medicine for sale?, Marcia Angell; Index.


    Kenneth D. Pimple, Dr and Professor, Director of Teaching Research Ethics Programs, Poynter Center for the Study of Ethics and American Institutions, Indiana University Center for Bioethics, Indiana University, USA.

    ' excellent and useful reference for those academics, professionals and students engaged in the study and examination of research ethics irrespective of whether they are new to the field or have an established interest in it. ' Public Health Ethics '...invaluable as a source of inspiration and challenge to any student or professional engaged in a study of research ethics...' Research Ethics Review 'There is much of interest and value in this collection...' Cyrstallography Reviews