The most authoritative and comprehensive guide on RLS to date, this expertly written source examines the pathogenesis, diagnosis, and treatment of a condition affecting nearly 10% of the population. Ranging from basic science to therapeutics, Restless Legs Syndrome analyzes the many new and emerging medications impacting the management of this disorder and strives to address the explosion of research in the field.
Overview of Sleep. The Brain's Dopamine Systems. Circadian Physiology. Systemic Iron Regulation. The Physiology of RLS. Progress in the Animal Modeling of RLS. Pathology of RLS. Genetics of RLS. Consequences of Sleep Deprivation. Diagnostic Criteria and Differential Diagnosis. Occurrence of RLS. Childhood-Onset RLS. Periodic Limb Movement of Sleep. Quality of Life in RLS. Patient Perspectives. Iron Deficiency-Associated RLS. Renal Failure. Neuropathy/Myelopathy. Pregnancy. Parkinson's Disease. Iatrogenic RLS. Other RLS Associations. Treatment Overview. Dopaminergic Treatment of RLS. Dopaminergic Augmentation. Opioid Treatment of RLS. Iron Therapy in RLS. Other Therapies in RLS. Future Directions.