This book describes the role of the obligate inhabitants of all vertebrate genomes—endogenous retroviruses, especially those emerged in genomes rather recently, during primate evolution. It specially focuses on human endogenous retroviruses as well as other retroelements.
1. A Glance at Evolution through the Genomic Window 2. Complex Genome Comparisons: Problems and Approaches 3. A Brief Introduction to Primate Evolution 4. How Different Is the Human Genome from the Genomes of the Great Apes? 5. Retroviruses, Their Domesticated Relatives and Other Retroinvaders: Potential Genetic and Epigenetic Mediators of Phenotypic Variation 6. Genomic Distributions of Human Retroelements 7. Influence of Human Endogenous Retroviruses on Cellular Gene Expression 8. Genome-Wide Search for Human Specific Retroelements 9. Genome-Wide Analysis of Human Gene Expression: Application to the Expression of Human Endogenous Retroviruses 10. Phylogeny of Human Endogenous and Exogenous Retroviruses 11. Evolutionary Aspects of Human Endogenous Retroviral Sequences (HERVs) and Disease