Cannabis Physiopathology and Detection features an outstanding collection of contributions from leading researchers around the world. Papers were presented at the Second International Colloquium on Illicit Drugs, held at the French National Academy of Medicine in April 1992. The book reviews the latest clinical reports describing the effects of cannabis on the brain (imaging techniques, memory and psychomotor performance, cannabis, and schizophrenia), effects on reproduction (male and female), and carcinogenicity. Aspects of detection covered in the volume include methods, results of different testing groups, and legal issues associated with testing and detection.
Cannabis Physiopathology and Detection will be an important addition to the reference collections of marijuana researchers, pathologists, government agencies, medical school libraries, and drug testers.
Table of Contents
PHYSIOPATHOLOGY. TOXICOLOGY. General Toxicity of Cannabis (G. Nahas). VISUALIZATION OF BRAIN ALTERATIONS. Use of Positron Emission Tomography to Study Drugs of Abuse (N. Volkow). EFFECTS ON PSYCHOMOTOR PERFORMANCE. Marijuana Carry-Over Effects on Psychomotor Performance: A Chronicle of Research (V.O. Leirer). Chronic Marijuana Smoking and Short-Term Memory Impairment (R.H. Schwartz). Detection of Cannabis and Other Drugs in 120 Victims of Road Accidents (M. Aussedat and S. Niziolek-Reinhardt). Marijuana and Alcohol Use among 1023 Trauma Patients (C.A. Soderstrom, A. Trifillis, B. Shankar, W. Clark, and A. Cowley). PSYCHOPATHOLOGY AND BEHAVIOR. Historical Outlook of the Psychopathology of Cannabis (G. Nahas). Prospective Study of 104 Psychiatric Cases Associated with Cannabis Use in a Moroccan Medical Center (T. Chkili and J.E. Ktiouet). Effects of Cannabis on Schizophrenia (J.C. Negrete). Schizophrenia and Cannabis: Cause-Effect Relationship? (P. Allebeck). Schizophrenia and Cannabis. How Causal a Relationship? (B. Defer). Cannabis-Associated Deaths in Medico-Legal Postmortem Studies. Preliminary Report (J. Rajs). EFFECTS ON IMMUNE FUNCTION AND CARCINOGENESIS. Delta-9-Tetrahydrocannabinol Suppresses Macrophage Extrinsic Anti-Herpes Virus Activity (G. Cabral and R. Vasquez). A Case-Control Study of Acute Nonlymphoblastic Leukemia—Evidence for an Association with Marijuana Exposure (J. Buckley). Marijuana and Upper Aerodigestive Tract Malignancy in Young Patients (P.J. Donald). EFFECTS ON REPRODUCTIVE FUNCTION. Effects of Cannabis on Reproduction (H. Tuchmann-Duplessis). EPIDEMIOLOGY. UNITED STATES. Report from North America (M. Rosenthal). Medical Aspects of Cannabis Abuse in Latin America (R. Jeri). Trends and Policies Regarding Cannabis and Other Narcotics in Sweden (P. Allebeck). Cannabis Consumption in the French Population (12 to 44 Years Ago) in 1991 (L. Gaillaud). The Epidemiology of Adolescent Drug Use in France and Israel (D. Kandel, I. Adler, and M. Sudit). Drug Reform: The Dutch Experience (R.H. Schwartz). The Dutch Drug Policy: A Physician's Commentary (K.F. Gunning). Cannabis and the Law (G. Lagier and J. Michaud). Cannabis: Point of View of W.H.O. (J. Idanpaan-Heikkila). DETECTION, IDENTIFICATION, AND TESTING. IDENTIFICATION AND DETECTION. Identification and Measurement of Cannabinoids and Their Metabolites in Biological Fluids (P. Levillain). Detection of Illegal Drugs in Body Fluids and Interpretation of Results (P. Lafargue). Salivary THC Following Cannabis Smoking Correlates with Subjective Intoxication and Heart Rate (D. B. Menkes, R. Howerd, G. Spears, and E. Cairns). TESTING. Testing for Illicit Drugs in the Workplace (P. Bensinger). Screening Students for Cannabis (R.H. Schwartz). Testing for Drugs in the Military and Transportation Industry (P. Mullory). Drug Use and Drug Detection in the French Armed Forces (P. Juillet). General Conclusions (H. Baylon). APPENDIX. Hashish and Mental Illness. The Experience and Observations of Moreau (H. Peters). Effects of THC on the Brain and Social Organization of Ants (P. Waser). Drug Use and the Lognormal Distribution (W. D. Paton). The Distribution of Consumption of Marijuana and Alcohol (G.G. Nahas and C. Latour). The London Times, July 24, 1992 (Just Say Now). The Swedish Addiction Epidemic in Global Perspective (N. Bejerot). INDEX.
Gabriel G. Nahas, M.D., Ph.D. was Professor of Anesthesiology at Columbia University College of Physicians and Surgeons.