Provides a multidisciplinary approach to the study of energetics of secretion responses by combining the knowledge and expertise of leading authorities from various fields.
Table of Contents
Energy-Dependent-Steps in Signal Processing: Calcium Mobilization (W. Siffert). The Role of Protein Kinase C in Secretory Responses (K. Ase, H. Nomura, M. go, T. hashimoto, K. Ogita, U. Kikkawa, and Y. Nishizuka). The Redox Potential (W.J. Malaisse and A. Sener). Energy-Requirement of Exocytosis: Chemiosmotic Events (K.W. Brocklehurst and H.B. Pollard). Membrane Interaction and Fusion (J. Wilschut). The Role of the Actomyosin System in Secretion (J.L. Daniel). Energy Metabolism during Secretion: Alterations in Energy Metabolism in Secretory Cells (U. Panten and S. Lenzen). The Energy Requirement of Secretion (J.-W. Akkerman). Index.
Jan-Willem N. Akkerman PhD is the Director of the Laboratory of Haematology in the Department of Haematology at the University of Utrecht, The Netherlands. He received his Ph.D. degree in 1975 on a thesis entitled "Human Platelet Glycolysis" and was a visiting staff member at the Thrombosis Research Center at Temple University, Philadelphia, Pa. In 1978.
His research efforts are in the field of thrombosis and atherosclerosis, with special emphasis on the role of blood platelets and the mechanisms that make these cells responsive to platelet-activating agents. His current research interests are the energetics of platelet functions, mechanisms for signal transduction, and abnormal platelet behaviour in patients with bleeding disorders or hyperaggregability.