Intended for cell biologists, biophysicists, biochemists, molecular biologists, physiologists, researchers in hemostatsis and thrombosis and pathologists, this book provides an insight into cell adhesion from three interdisciplinary perspectives: fundamental facts of adhesion; molecular biochemistry of adhesion and physiological aspects. It summarizes the basic aspects of surfaces in general and describes the theoretical and experimental tools necessary to investigate cell adhesion, including the basic biochemistry and molecular biology of adhesion. The book offers concise treatment of individual topics, features current material, and provides key references as a guide to further study.
SECTION I: Fundamental Facets of Adhesion 1. Physical and Molecular Biochemical Aspects of Cell Adhesion: Viewpoints Approaching a Mutual Understanding Peter D. Richardson 2. Biomechanics and Thermodynamics of Cell Adhesion Cheng Zhu 3. Influences of Surface Chemical Factors on Selective Cellular Retention Robert E. Baier, Karen H. Rittle, and Anne E. Meyer 4. Dictyostelium discoideum Cohesion and Adhesion Donna R. Fontana 5. Adhesive Properties of Bacteria Josef Beuth and Gerhard Uhlenbruck 6. Bioadhesives: DOPA and Phenolic Proteins as Components of Organic Composite Materials Leszek M. Rzepecki, Karolyn M. Hansen, and J. Herbert Waite 7. Flow Effects on Leukocyte Adhesion to Vascular Endothelium Divid A. Jones, C. Wayne Smith, and Larry V. McIntire SECTION II: The Molecular Biochemistry of Adhesion 8. The Integrin Cell Adhesion Molecules Jonathan M. Edelman, Paul A. DiMilla, and Steven M. Albelda 9. The Structure and Biological Function of the Neural Cell Adhesion Molecule N-CAM John J. Hemperly 10. The Selectin Family of Adhesion Molecules Eric Larsen 11. Structure and Assembly of Basement Membrane and Related Extracellular Matrix Konrad Beck and Tanja Gruber 12. The Interaction of the Cytoskeleton with Adhesive Receptors: Effects on Cell Adhesion Joan E. B. Fox SECTION III: Physiology of Adhesion 13. Homing of Cells: Stem Cell as a Model Mehdi Tavassoli (Posthumous) 14. Platelet Aggregation and Inhibitors Kailash C. Agarwal 15. Platelet Adhesion Manfred Steiner 16. Interactions Among Platelets, Tumor Cells, and the Vessel Wall Kenneth V. Honn, Yong Q. Chen, and Dean G. Tang 17. Pharmacological Intervention of Platelet Adhesion Doloretta Dawicki 18. Platelet Adhesion to Damaged Vessel Wall S. Fazal Mohammad Index