1st Edition
Rewriting Cancer Fields, Metabolism, and the Reversibility of Malignant Transformation
Rewriting Cancer synthesizes a unified framework and derives a practical therapeutic protocol for cancer — one that uses repurposed, off-patent drugs to normalize the tumor microenvironment rather than simply kill cancer cells.
Part I — Foundations 1. The Fifty-Year War: Successes, Limits and Open Questions in Oncology 2. The Genetic Paradigm: Successes and Limits 3. The Economic-Scientific System of Oncology Research: Understanding the Context Part II — Three Biological Pillars 4. Tissue Bioelectricity and the Field-Level Account 5. Cellular Metabolism: Warburg Revisited 6. The Tumour Microenvironment Part III — Integrative Treatment Protocols 7. Integrative Protocols: Glioblastoma Multiforme 8. Integrative Protocols: Advanced Melanoma 9. Integrative Protocols: Metastatic Colorectal Cancer 10. Pre-clinical Drug Repurposing 11. Clinical Evidence and the Coley Tradition Part IV — Five Pillars 12. Introduction to the Five Pillars 13. P1 — Membrane Repolarisation 14. P2 — Therapeutic Apheresis in Oncology 15. P3 — Ozone Therapy and Artesunate as Candidate Adjunct 16. P4 — Metabolic Blockade 17. P5 — Nutritional Reprogramming Part V — Clinical Application 18. Patient Selection and Drug Interactions 19. The 105-Day Protocol: Architectural Framework for Prospective Evaluation 20. Monitoring and Biomarkers 21. Integration with Conventional Therapies Information Classification: General Part VI — Synthesis 22. Synthesis: Platform-Trial Architecture, Regulatory Pathway, and the Prospective□Evaluation Programme
Biography
Giovanni Ziliani (Brescia, Italy, 1963) is an industrial chemist, inventor, and published author whose career has woven together three disciplines: engineering, biology, and medicine. He is the author of 9 books. He holds 6 patents.
