1st Edition

Rodent Models of Neurodegenerative Disease

Edited By Pegah Javadpour, Rasoul Ghasemi Copyright 2026
162 Pages 19 Color & 1 B/W Illustrations
by CRC Press

162 Pages 19 Color & 1 B/W Illustrations
by CRC Press

Rodent Models of Neurodegenerative Disease explores neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, frontotemporal dementia, Lewy body disease, and prion disease which represent some of the most complex and devastating challenges in neuroscience. With rising prevalence in aging populations worldwide, these... Read more

Chapter I Introduction to Animal Models in Neurodegenerative Research: Bridging the Gap Between Lab and Clinic Chapter 1 Rodent Models of Alzheimer’s Disease Chapter 2 Rodent Models of Parkinson’s Disease Chapter 3 Rodent Models of Amyotrophic Lateral Sclerosis Chapter 4 Rodent Models of Frontotemporal Dementia Chapter 5 Rodent Models of Lewy Body Disease Chapter 6 Rodent Models of Huntington’s Disease Chapter 7 Rodent Models of Prion Disease Chapter 8 Behavioral Assays in Rodent Models: Methods for Assessing Motor, Cognitive, and Social Phenotypes

Biography

Dr. Pegah Javadpour, PhD, is Assistant Professor of Medical Physiology at the Neuroscience Research Center, Institute of Neuroscience and Cognition, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Her research focuses on mitochondrial dysfunction, oxidative stress, and neuroinflammation in neurodegenerative disorders, particularly Parkinson’s and Alzheimer’s diseases. She has a special interest in mitochondria-targeted therapeutic strategies, including mitochondrial transplantation therapy (mitotherapy), as potential treatments for these conditions.

Dr. Rasoul Ghasemi, PhD, is Associate Professor of Physiology in the Department of Physiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. His research explores the neurophysiology of learning and memory, with emphasis on insulin signaling, hippocampal function, neuroinflammation, oxidative stress, and neuroprotection in neurodegenerative diseases. He has published extensively on the cellular and molecular mechanisms underlying brain resilience and pathology.