856 pages | 133 B/W Illus.
This reference serves as the most current and comprehensive source on the many aspects of sarcoidosis ranging from the basic science and pathophysiology of the disease to patient evaluation and treatment-providing a detailed analysis of the pulmonary aspects of the condition including chapters on radiographic manifestations, bronchoalveolar lavage research, pulmonary function studies, and proposed markers for the diagnosis and management of the disease.
"…The book summarizes current understanding of the molecular and immunologic basis of sarcoidosis; further, it broadly surveys the prtean presentations of the disease which remains of unknown cause. It appears to be novel as a comprehensive work linking basic science to a broad all-inclusie array of clinical pulmonary medicine entities."
Historical Perspective. General Approach to Epidemiology. What the New Studies are Telling Us. Mechanism of Granuloma Formation. Lymphocytic Aspects. Antigen-Presenting Cells. Cytokines/Chemokines. The Kviem Reaction. Familial Sarcoidosis. HLA Patterns and Risk for Sarcoidosis. Effect of Fenetic Pattern on Subsequent Form of Sarcoidosis. The Search for the Potential Pathogen. Propionobacteria as a cause of Sarcoidosis. Hypersensitivity Pneumonitis. Beryllium as a Model for Sarcoidosis. Clinical Presentation. Radiographic Images in Sarcoidosis. BAL in Sarc. PRTs including Exercise Physiology. Markers of Disease. Quality of Life. Pathology and Evaluation for Mycobacterial Disease. Neurologic Disease. Cardiac Disease. Ocular Disease. Hepato-splenic Disease. Dermatologic Disease. Skeletal. Calcium Metabolism. Rare Forms of Sarcoidosis. Mechanisms of Therapy. Corticosteroids for Therapy. Steroid Alternatives for Sarc. Transplant. Etiology: Putting it All Together. Therapy of Sarcoidosis