8th Edition
Scott-Brown's Otorhinolaryngology and Head and Neck Surgery Volume 1: Basic Sciences, Endocrine Surgery, Rhinology
Cell biology
1: Molecular biology
Michael Kuo, Richard M. Irving and Eric K. Parkinson
2: Genetics in otology and neurotology
Mohammed-Iqbal Syed
3: Gene therapy
Seiji B. Shibata and Scott M. Graham
4: Mechanisms of anticancer drugs
Sarah Payne and David Miles
5: Radiotherapy and radiosensitizers
Christopher D. Scrase, Stewart G. Martin and David A.L. Morgan
6: Apoptosis and cell death
Angela Hague
7: Stem cells
Navin Vig and Ian C. Mackenzie
8: Aetiology and pathogenesis of goitre
Neil Sharma and Kristien Boelaert
9: Genetics of endocrine tumours
Waseem Ahmed, Prata Upasna and Dae Kim
Wound healing
10: Soft and hard tissue repair
Sarah Al-Himdani and Ardeshir Bayat
11: Skin flap physiology
Colin MacIver and Stergios Doumas
12: Biomaterials, tissue engineering and their application in the oral and maxillofacial region
Kurt Busuttil Naudi and Ashraf Ayoub
Immunology
13: Defence mechanisms
Ian Todd and Richard J. Powell
14: Allergy: Basic mechanisms and tests
Sai H.K. Murng
15: Evaluation of the immune system
Moira Thomas, Elizabeth Drewe and Richard J. Powell
16: Cancer immunology
Osama Al Hamarneh and John Greenman
17: Human papillomavirus
Mustaffa Junaid and Hisham M. Mehanna
18: Connective tissue diseases: ENT complications
Eileen Baildam
Microbiology
19: Microorganisms
Ursula Altmeyer, Penelope Redding and Nitish Khanna
20: Viruses and antiviral agents
Richard B. Townsley, Camille A. Huser and Chris Hansell
21: Fungal infections
Emily Young, Yujay Ramakrishnan, Laura Jackson and Shahzada K. Ahmed
22: Antimicrobial therapy
Ursula Altmeyer, Penelope Redding and Nitish Khanna
23: Human immunodeficiency virus
Neil Ritchie and Alasdair Robertson
Haematology
24: Blood groups, blood components and alternatives to transfusion
Samah Alimam, Kate Pendry and Michael F. Murphy
25: Haemato-oncology
Robert F. Wynn and Mark Williams
26: Haemostasis: Normal physiology, disorders of haemostasis and thrombosis
Elizabeth Jones and Russell David Keenan
Pharmacotherapeutics
27: Drug therapy in otology
Wendy Smith
28: Drug therapy in rhinology
Wendy Smith
29: Drug therapy in laryngology and head and neck surgery
Wendy Smith and Rogan Corbridge
Perioperative management
30: Preparation of the patient for surgery
Michael Murray and Urmila Ratnasabapathy
31: Recognition and management of the difficult airway
Valerie Cunningham and Alistair McNarry
32: Adult anaesthesia
Daphne A. Varveris and Neil G. Smart
33: Adult critical care
Robert I. Docking and Andrew Mackay
34: Paediatric intensive care
Louise Selby and Robert Ross Russell
Safe and effective practice
35: Training, accreditation and the maintenance of skills
B. Nirmal Kumar, Andrew Robson, Omar Mirza and Baskaran Ranganathan
36: Communication and the medical consultation
Uttam Shiralkar
37: Clinical governance and its role in patient safety and quality improvement
Samit Majumdar and S. Musheer Hussain
38: Medical ethics
Paul Baines
39a: Medical jurisprudence in otorhinolaryngology
Maurice Hawthorne
39b: Medical negligence in otorhinolaryngology
Maurice Hawthorne
40: Non-technical skills for ENT surgeons
Simon Paterson-Brown and Stephen R. Ell
Interpretation and management of data
41: Epidemiology
Jan H.P. van der Meulen, David A. Lowe and Jonathan M. Fishman
42: Outcomes research
Iain R.C. Swan and William Whitmer
43: Evidence-based medicine in medical education and clinical practice
Phillip Evans
44: Critical appraisal skills
Paul Nankivell and Christopher Coulson
Advances in technology
45: Electrophysiology and monitoring
Patrick R. Axon and Bruno M.R. Kenway
46: Optical coherence tomography
Jameel Muzaffar and Jonathan M. Fishman
47: Recent advances in technology
Wai Lup Wong and Bal Sanghera
48: Image-guided surgery, 3D planning and reconstruction
Ghassan Alusi and Michael Gleeson
49: Interventional techniques
James V. Byrne
50: Laser principles in otolaryngology, head and neck surgery
Brian J.G. Bingham
51: Contact endoscopy of the upper aerodigestive tract
Mario Andrea and Oscar Dias
Section 2 Head and Neck Endocrine Surgery
Overview
52: History of thyroid and parathyroid surgery
Waraporn Imruetaicharoenchoke, Ashok R. Shaha and Neil Sharma
53: Developmental anatomy of the thyroid and parathyroid glands
Julian A. McGlashan
54: Developmental anatomy of the pituitary fossa
John Hill and Sean Carrie
55: Physiology of the thyroid and parathyroid glands
Martin O. Weickert
56: Physiology of the pituitary gland
Mária Hérincs, Karen Young and Márta Korbonits
57: Imaging in head and neck endocrine disease
Steve Colley and Sabena Fareedi
58: Thyroid and parathyroid gland pathology
Ram Moorthy, Sonia Kumar and Adrian T. Warfield
Thyroid disease
59: Clinical evaluation of the thyroid patient
Andrew Coatesworth and Sebastian Wallis
60: Investigation of thyroid disease
Anthony P. Weetman
61: Benign thyroid disease
Christopher M. Jones and Kristien Boelaert
62: Management of differentiated thyroid cancer
Hisham M. Mehanna, Kristien Boelaert and Neil Sharma
63: Management of medullary thyroid cancer
Barney Harrison
64: Management of anaplastic thyroid cancer/lymphoma
James D. Brierley and Richard W. Tsang
65: Management of locoregionally recurrent differentiated thyroid cancer
Iain J. Nixon and Ashok R. Shaha
66: Non-surgical management of thyroid cancer
Laura Moss
Thyroid surgery
67: Thyroidectomy
Ricard Simo, Iain J. Nixon and Ralph P. Tufano
68: Surgery for locally advanced and nodal disease
Joel Anthony Smith and John C. Watkinson
69: Minimally invasive and robotic thyroid surgery
Neil S. Tolley
70: Surgery for the enlarged thyroid
Neeraj Sethi, Josh Lodhia and R. James A. England
Parathyroid disease
71: Clinical evaluation of hypercalcaemia
Mo Aye and Thozhukat Sathyapalan
72: Investigation of hyperparathyroidism
M. Shahed Quraishi
73: Management of hyperparathyroidism
Neil J.L. Gittoes and John Ayuk
74: Management of persistent and recurrent hyperparathyroidism
David M. Scott-Coombes
75: Management of parathyroid cancer
Pamela Howson and Mark Sywak
Parathyroid surgery
76: Bilateral parathyroid exploration
R. James A. England and Nick McIvor
77: Minimally invasive parathyroidectomy
Parameswaran Rajeev and Gregory P. Sadler
78: Surgical failure and reoperative surgery
Schelto Kruijff and Leigh Delbridge
Thyroid and parathyroid outcomes
79: Complications of thyroid and parathyroid surgery and how to avoid them
Erin A. Felger, Dipti Kamani and Gregory W. Randolph
80: Thyroid and parathyroid surgery: Audit and outcomes
David Chadwick
81: Medicolegal aspects of head and neck endocrine surgery
Barney Harrison
Pituitary disease
82: Clinical evaluation of the pituitary patient
Sean Carrie, John Hill and Andrew James
83: Investigation of pituitary disease
Thozhukat Sathyapalan and Stephen L. Atkin
84: Primary pituitary disease
Christopher M. Jones and John Ayuk
85: Surgical management of recurrent pituitary tumours
Mihir R. Patel, Leo F.S. Ditzel Filho, Daniel M. Prevedello, Bradley A. Otto and Ricardo L. Carrau
86: Adjuvant treatment of pituitary disease
Andy LevySection 3 Rhinology
87: Anatomy of the nose and paranasal sinuses
Dustin M. Dalgorf and Richard J. Harvey
88: Outpatient assessment
Martyn L. Barnes and Paul S. White
89: Physiology of the nose and paranasal sinuses
Tira Galm and Shahzada K. Ahmed
90: Measurement of the nasal airway
Ron Eccles
91: Allergic rhinitis
Quentin Gardiner
92: Non-allergic perennial rhinitis
Jameel Muzaffar and Shahzada K. Ahmed
93: Occupational rhinitis
Hesham Saleh
94: Rhinosinusitis: Definitions, classification and diagnosis
Carl Philpott
95: Nasal polyposis
Louise Melia
96: Fungal rhinosinusitis
Eng Cern Gan and Amin R. Javer
97: Medical management for rhinosinusitis
Claire Hopkins
98: Surgical management of rhinosinusitis
A. Simon Carney and Raymond Sacks
99: The frontal sinus
Salil Nair
100: Mucoceles of the paranasal sinuses
Darlene E. Lubbe
101: Complications of rhinosinusitis
Stephen Ball and Sean Carrie
102: The relationship between the upper and lower respiratory tract
Nigel K.F. Koo Ng and Gerald W. McGarry
103: Nasal septum and nasal valve
Shahram Anari and Ravinder Singh Natt
104: Nasal septal perforations
Charles East and Kevin Kulendra
105: Management of enlarged turbinates
Andrew C. Swift and Samuel C. Leong
106: Epistaxis
Gerald W. McGarry
107: Nasal and facial fractures
Dae Kim and Simon Holmes
108: CSF leaks
Scott M. Graham
109: Granulomatous conditions of the nose
Joanne Rimmer and Valerie J. Lund
110: Abnormalities of smell
Richard L. Doty and Steven M. Bromley
111: Disorders of the orbit
Nithin D. Adappa and James N. Palmer
112: Diagnosis and management of facial pain
Rajiv K. Bhalla and Timothy J. Woolford
113: Juvenile angiofibroma
Bernhard Schick
114: Endoscopic management of sinonasal tumours
Alkis J. Psaltis and David K. Morrissey
115: Surgical management of pituitary and parasellar diseases
Philip G. Chen and Peter-John Wormald
116: Extended anterior skull base approaches
Carl H. Snyderman, Paul A. Gardner, Juan C. Fernandez-Miranda and Eric W. Wang
117: Imaging in rhinology
Gregory O’Neill
Index
Biography
Editors
John C Watkinson MSc (Nuclear Medicine; London). MS (London). FRCS (General Surgery). FRCS(ENT). DLO.
One-Time Honorary Senior Lecturer and Consultant ENT/Head and Neck and Thyroid Surgeon. Queen Elizabeth Hospital, University of Birmingham NHS Trust and the Royal Marsden and Brompton Hospitals, Fulham Road, Chelsea, London, UK.
Currently Honorary Consultant ENT/Head and Neck and Thyroid Surgeon. Great Ormond Street Hospital (GOSH) and St Georges Hospital NHS Trust, Tooting, London.
Honorary Senior Anatomy Demonstrator, University College London (UCL).
Business Director, Endocrine MDT. The Bupa Cromwell Hospital, Kensington, London.
Raymond W Clarke BA, BSc, DCH, FRCS, FRCS(ORL)
Consultant Paediatric Otolaryngologist, Royal Liverpool Children’s Hospital, Liverpool UK, Senior Lecturer and
Associate Dean, University of Liverpool, UK
Section Editors
Louise Jayne Clark MB ChB, MD (dist), FRCS (ORL), FRCS (ENT).
Queen Elizabeth University Hospital, Glasgow UK
Adam J Donne, FRCS,
Consultant Paediatric ENT Surgeon, Alder Hey, Liverpool, UK
R. James A. England
Consultant Otolaryngologist Head and Neck Surgeon, Honorary Senior Lecturer
Hull and East Yorkshire NHS Hospitals Trust & Hull University, UK
Prof Hisham M Mehanna PhD, BMedSc (hons), MBChB (hons), FRCS, FRCS (ORL-HNS)
Chair of Head and Neck Surgery and Director of the Institute of Head and Neck Studies and Education, at the School
Cancer Sciences, University of Birmingham, UK
Gerald William McGarry MB.ChB. MD. FRCSEd. FRCS(ORL-HNS) FFSTEd
Consultant Surgeon Head and Neck and Anterior Skull Base Surgery.
Glasgow Royal infirmary, Greater Glasgow and Clyde NHS
Hon.Clinical Senior Lecturer, University of Glasgow
Sean Carrie, FRCS,
Consultant Otolaryngologist / Skull base Surgeon, Newcastle upon Tyne Hospitals NHS Foundation Trust and Hon
Senior Clinical Lecturer, Newcastle University, UK
