1st Edition

Self-Organized 3D Tissue Patterns Fundamentals, Design, and Experiments

By Xiaolu Zhu, Zheng Wang Copyright 2022
148 Pages 15 Color & 18 B/W Illustrations
by Jenny Stanford Publishing

148 Pages 15 Color & 18 B/W Illustrations
by Jenny Stanford Publishing

Therapies for regenerating damaged tissue and organs have been attracting much attention. In order to efficiently regenerate the functions of living tissue and organs, diverse attempts have been made to utilize scaffolds to “mold” artificial tissue structures. However, the structural complexity of reconstituted tissue is limited by the mechanical precision of scaffolds, which still cause problems... Read more
1. Introduction  2. Fundamentals of Three-Dimensional Cell Culture in Hydrogels  3. Three-Dimensional Patterns of Tissues Emerging in Hydrogels  4. Constructing 3D Tissue Structures via Cellular Self-Assembly at Patterned Interfaces inside Hydrogel  5. Modeling Cellular Self-Assembly at Patterned Interfaces inside Hydrogel via Turing’s Reaction-Diffusion Frame  6. Tuning Cellular Behaviors during Self-Organization of Cells in Hydrogel by Changing Inner Nano-Structure of Hydrogel 

Biography

Xiaolu Zhu is Associate Professor at Hohai University, China. He graduated from Southeast University, China, in 2007 and obtained a PhD in 2014. He worked as a research scholar at the University of California, Los Angeles, from 2011 to 2013. His work is currently focused on understanding and controlling self-organized 3D patterns of cells and hydrogel-based biofabrication.

Zheng Wang is currently a master’s student at the University of Hong Kong. He obtained his bachelor’s degree from Hohai University in 2020. He is working on the development of the applications of hydrogels in the regulation of cellular behaviors and on the quantification of the relationships between cellular behaviors and the physical properties of the extracellular matrix.