Sensitization is a concept of learning and memory that has grown out of experiments on "simple" animals. Interest in sensitization has grown tremendously in the last several years, fueled mainly by evidence of the molecular basis of sensitization in invertebrates on the one hand and the study of cocaine abuse, which produces behavioral sensitization, on the other. Because the rapid advance of information across such a broad range of research areas has made an integrated approach necessary, this volume combines findings on sensitization across the phylogenetic scale.
The Development of Sensitization in Aplysia (Catharine H. Rankin, Thomas G. Nolen, Emilie A. Marcus, Mark Stopfer and Thomas J. Carew). Sensitization and Dishabituation: Extension of a Behavioral Distinction to the Molecular Level (Marc Klein). Hippocampal Long-Term Potentiation (John M. Sarvey). Characteristics and Mechanisms of Kindling (Michael E. Corcoran). Sensitization of Mesolimbic Dopamine Neurons By Neuropeptides and Stress (Peter W. Kalivas, Patricia Duffy, Raymond Abhold and Roger P. Dilts). Stimulant Drugs and Stress: Factors Influencing Individual Differences in the Susceptibility to Sensitization (Terrence E. Robinson). Psychomotor Stimulant-Induced Sensitization: Behavioral and Neurochemical Correlates (Ronald Kuczenski and David S. Segal). Conditioning and Behavioral Sensitization (Jane Stewart and Paul Vezina). Stressor-Induced Sensitization to Subsequent Stress: Implications for the Development and Treatment of Clinical Disorders (Seymour M. Antelman). Sensitization and Kindling: Implications for the Evolution of Psychiatric Symptomatology (Robert M. Post and Susan R.B. Weiss). Index.