1st Edition
Sickle Cell Disease in Sub-Saharan Africa Biomedical Perspectives
This important collection provides an epidemiological perspective on the continuing scope of sickle cell disease (SCD) in sub-Saharan Africa, alongside the clinical attempts to provide comprehensive care in a resource-limited setting.
The book moves from a clinical profile of SCD to screening for the disease and ongoing patient care. There are chapters on pain management, organ failure, infections and transfusions, as well as nutrition and neurocognitive complications. The book concludes with chapters on anti-sickness medication, cell transplantation and nursing care.
The first in a two-volume set offering a multi-disciplinary perspective on SCD, this is a comprehensive resource that applies clinical knowledge to the practical challenges faced in sub-Saharan Africa. It will be important reading for medical students taking courses in haematology as well as those studying Public Health in sub-Saharan Africa. Practitioners in the region will also find it invaluable in developing their understanding of this pervasive disease.
Introduction
Baba Inusa, Kanayo Nwankwo, Nkechi Azinge-Egbiri and Bukola Bolarinwa
Chapter 1 - The Clinical Epidemiology of Sickle Cell Disease in Sub-Saharan Africa
Thomas N Williams
Chapter 2 - Laboratory Profile of Sickle Cell Disease
Nwabundo I. Anusim and Ugochi O. Ogu
Chapter 3 - Pre-implantation Genetic Diagnosis for Prevention of Sickle Cell Disorder: Current Trends and Barriers
Annette Akinsete
Chapter 4 - The State of Newborn Screening for Sickle Cell Disease in Low and Middle
Income Countries
Baba Inusa, Juliana Olufunke Lawson, Livingstone Dogara and Lewis Hsu
Chapter 5 - Routine Comprehensive Care for Children with SCD
Nnenna Ukachi Badamosi
Chapter 6 - Pediatric to Adult Transition Care for Patients with Sickle Cell Disorder
Tamunomieibi Wakama and Ekaete David
Chapter 7 - Neurocognitive Complications of Sickle Cell Disease in Africa
Fenella Kirkham, Mary Ampomah, Mboka Jacob, Maryam Shehu, Dawn E. Saunders, Richard Idro and Ikeola Lagunju
Chapter 8 - Overview of Organ Dysfunction in Sickle Cell Disease
Ruth Namazzi, Catherine Nabaggala, Annet Nakirulu, Philip Kasirye and Deogratais Munube
Chapter 9 - Management of Pain in Sickle Cell Disease
Ademola Samson Adewoyin
Chapter 10 - Management of Infections and Fever in Sickle Cell Disease (SCD)
Ahmed M Sarki, Lilian Nuwabaine and Sabrina Bakeera-Kitaka
Chapter 11 - Transfusion in Sickle Cell Disease (SCD): Complications Including Iron Overload
Kanayo Nwankwo and Sophie Uyoga
Chapter 12 - Pregnancy in women with Sickle Cell Disorder
Bosede B. Afolabi
Chapter 13 - Sickle Cell Disease and Nutrition
Vivian Omuemu
Chapter 14 - Hydroxyurea in the management of Sickle Cell Disease in Africa
Léon Tshilolo
Chapter 15 - Niprisan and Other Homegrown Antisickling Medications: Successes and Challenges
Oluseyi Oniyangi and Ugochi O. Ogu
Chapter 16 - Investigational Therapies and Advances in Science for SCD: A Glimmer of Hope
Dunia Hatabah and Miguel Abboud
Chapter 17 - Hematopoietic Cell Transplantation for Sickle cell Disease: A global perspective
Sarita Rani Jaiswal and Suparno Chakrabarti
Chapter 18 - Nursing Care in Sickle Cell Disease: Lessons from East Africa
Eunice Ndirangu-Mugo
Chapter 19 - Access to Blood Products for SCD Warriors in Nigeria - Challenges and Opportunities
Adaeze Oreh
Biography
Baba Inusa, MBBS (ABU 1984), FMCPaed (Nigeria, 1992), FRCPCH (UK, 1997) is Professor of paediatric haematology, Evelina London Children’s Hospital, Guy’s and St Thomas NHS Foundation Trust.
Kanayo Nwankwo, MD, is the Chief Resident and a lifespan sickle cell advocate, currently serving at Brookdale University Hospital in Brooklyn NY.
Nkechikwu Azinge-Egbiri, LLB (Hons), BL, LLM, PhD (Warwick), is a Lecturer at the School of Law, Lancaster University and Founder of the Sickle Cell Aid Foundation (SCAF), a youth-led NGO she established to raise awareness of Sickle Cell Disease (SCD) and support those living with it.
Bukola Bolarinwa is a qualified legal practitioner with an LLM in International Economic Law from the University of Warwick and LLB from the University of Leicester.
