Signalling Pathways in Apoptosis
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Apoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body's defence mechanisms against disease. Too much cell death is destructive, leading to neurodegenerative diseases and impaired development. Conversely, too litt
Table of Contents
1. The Role of Sphigolipids in Stress Responses and Apoptosis in Eukaryotes 2. Radiation Response Pathways and Apoptosis 3. Apoptosis in Drosophila 4. Baculoviral Lessons in Apoptosis 5. The Mitochondrion: Decisive for Cell Death Control? 6. Caspases and the Commitment to Death 7. Killer Cells - Deliverers of Exogenous Death Proteases 8. Protein Kinase C Isoenzymes: Evidence for Selectivity in the Regulation of Apoptosis 9, The Death Receptors 10. Kinase Cascades and Apoptosis 11. Caspases: The Molecular Effectors of Apoptosis 12.
Substrates of Cell Death Proteases and Their Role in Apoptosis