464 pages | 32 Color Illus. | 94 B/W Illus.
Since the potential toxicity of silver nanoparticles (Ag NPs) has raised serious concerns in the biomaterials and biomedical engineering community, Silver Nanoparticles for Antibacterial Devices: Biocompatibility and Toxicity brings togetherthe synthesis, the physicochemical properties and the biological actions of Ag NPs, as well as the clinical demands for fabricating antibacterial medical devices, discussing how to suppress the side effects of nanomaterials and how to impart to them the selective toxicity. This book presents the two primary paradigms that have emerged in probing the antibacterial applications of Ag NPs, i.e. the active attacking releasing way and the conservative defending approach by taking advantage of various short-range actions; it shows readers how the ways in which Ag NPs have behaved can be engineered purposively.
With contributions from leading international experts and extensive references listed in each chapter, this volume provides the general principles on controlling the physicochemical behaviors of nanomaterials and managing their toxicity risks.
SECTION I: Synthesis and Assembling
Chapter 1: Bioinspired Synthesis of Silver Nanoparticles: Characterization, Mechanism and Applications
Chapter 2: Tuning the Properties of Silver Monolayer for Biological Applications
Chapter 3: Synergistic Antimicrobial Activity of Silver and Chitosan
Chapter 4: Titania Nanotubes as Silver Nanoparticle Carriers to Prevent Implant-associated Infection
Chapter 5: Polymer-silver Nanocomposites: Preparation, Characterization and Antibacterial Mechanism
SECTION II: The Risk of Silver
Chapter 6: Dissolution of Silver Nanoparticles
Chapter 7: Silver as an antimicrobial agent: the Resistance Issue
Chapter 8: The Risks of Silver Nanoparticles to Human Body
Chapter 9: Imunomodulatory Activities of Silver nanoparticles (Ag NPs) in Human Neutrophils
SECTION III: Techniques and Concepts for Risk Control
Chapter 10: Evaluating the Interactions of Silver Nanoparticles and Mammalian Cells Based on Biomices Technologies
Chapter 11: Methods and Tools for Assessing Nanomaterials and Uses and Regulation of Nanosilver in Europe
Chapter 12: Toward Selectively Toxic Silver Nanoparticles
SECTION IV: Clinical Demands
Chapter 13: Orthopaedic Implant-associated Infections: Pathogenesis, Clinical Presentation and Management
Chapter 14: Dental Implant Infection: Typical Causes and Control
Chapter 15: Guidelines for Nanosilver-based Antibacterial Devices