Skin Immune System: Cutaneous Immunology and Clinical Immunodermatology, Third Edition, 3rd Edition (Hardback) book cover

Skin Immune System

Cutaneous Immunology and Clinical Immunodermatology, Third Edition, 3rd Edition

Edited by Jan D. Bos

CRC Press

840 pages | 83 B/W Illus.

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Hardback: 9780849319594
pub: 2004-10-28
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Top scientific authors contribute their expertise and put a wealth of complex information into perspective in Skin Immune System: Cutaneous Immunology & Clinical Immunodermatology, Third Edition. This edition provides an overview of the skin immune system (SIS), a totally updated section on immunodermatological diseases, and six new chapters.

Part I presents historical and comparative information on immunodermatology and includes a new chapter on the immunogenetics of inflammatory skin disease, while Part II covers the cellular elements of SIS and highlights newly defined functional subclasses of cells. Part III describes the humoral elements of SIS and provides two new chapters which focus on defensins and cathelicidins, and on the chemokines of human skin. Part IV discusses how the cellular and humoral elements of SIS interact under different circumstances and includes a new chapter on signal transduction pathways in cutaneous immunology. Part V focuses on dermatological diseases with a significant immunological background with a new chapter on the immunology of cutaneous drug eruptions, followed by Part VI on immunotherapy in dermatology, which features a new chapter reflecting the recent wave of products from biotechnology.

Since the publication of the previous editions, a great deal of significant information has become available in almost all areas of cutaneous immunology and clinical immunodermatology. This progress has now been reflected in a completely updated and expanded resource.


"…these chapters provide a well-worthwhile look at the work that has led up to our current understanding. The end result is a text that is well written and complete, yet easily manageable…a worthwhile addition to any library or collection."

European Journal of Dermatology, 2005

Table of Contents


Skin Immune System (SIS), Jan D. Bos

A History of Immunodermatology, Jan D. Bos

Comparative Immunology of the Integument, Edwin L. Cooper, Armando Péres, and Andrés Castell

The Immunogenetics of Inflammatory Skin Disease, William O.C.M. Cookson, Anne C. Bowcock, John I. Harper, and Miriam F. Moffatt


The Keratinocyte, Anthony C. Chu and Jenny F. Morris

Lymphocyte Subpopulations of the Skin, Andrea Cavani, Sergio Di Nuzzo, Giampiero Girolomoni, and Giuseppe De Panfilis

Langerhans Cells and Other Skin Dendritic Cells, Marcel B.M. Teunissen

Monocytes and Macrophages in Human Skin, Kurt Q. Lu, Thomas S. McCormick, Anita C. Gilliam, Kefei Kang, and Kevin D. Cooper

Endothelial Cells of Blood and Lymphatic Vessels, Krystyna A. Pasyk, George W. Cherry, and Barbara A. Jakobczak

Mast Cells, Maurice W. van der Heijden, Hanneke P.M. van der Kleij, Martin Röcken, and Frank A.M. Redegeld

Neutrophils, Eosinophils and Basophils in the Skin Immune System, Edward F. Knol, Taco W. Kuijpers, and Dirk Roos


Free Radicals, Maria Lucia Dell'Anna, Emanuela Camera, and Mauro Picardo

Defensins and Cathelicidins, Kevin O. Kisich and Donald Y.M. Leung

Complement as a Part of Skin Immune System, Syed Shafi Asghar, Krisztina K. Timar, and Marcel C. Pasch

The Skin Cytokine Network, Martin Steinhoff and Thomas A. Luger

Chemokines of Human Skin, Saveria Pastore, Andrea Cavani, Cristina Albanesi, and Giampiero Girolomoni

Neuropeptides in the Skin, James N. Baraniuk


Signal Transduction Pathways in the Skin, Lars Iversen and Knud Kragballe

Epidermis as a Pro-Inflammatory Organ, Jonathan Barker

Adhesion Molecules and Inflammatory Cell Migration Pathways in the Skin, Kenneth B. Gordon and Brian J. Nickoloff

Physiology and Pathology of Skin Photoimmunology, Sreedevi Kodali, Stephan Beissert and Richard D. Granstein

The Skin Immune System and Tumour Immunosurveillance, H. Konrad Muller, Gary M. Halliday, and Gregory M. Woods


Some Congenital Immunodeficiencies and their Dermatological Manifestations, J. Henk Sillevis Smitt

Immunobullous Diseases, Graham Ogg, Samantha Winsey, Sarah Wakelin, and Fenella Wojnarowska

Lichen Planus & Graft-Versus-Host Disease, Henry J.C. de Vries, Bhupendra Tank, and Rick Hoekzema

Lupus Erythematosus, Jan D. Bos and Menno A. de Rie

Cutaneous Vasculitis, Cord Sunderkötter and Gerhard Kolde

Urticarial Vasculitis, Torsten Zuberbier, Norbert Haas, and Beate M. Henz

Immunological Mechanisms of Cutaneous Adverse Drug Eruptions, Ewa Guigné, Jean Revuz, and Jean-Claude Roujeau

Atopic Dermatitis, Kristian Thestrup-Pedersen

Allergic Contact Dermatitis, Pierre Saint-Mezard, Maya Krasteva, Frédéric Berard, Bertrand Dubois, Dominique Kaiserlian and Jean-François Nicolas

Psoriasis, Jörg Christoph Prinz

Viral Infections, Mary Norval

Fungal Infections, Roderick J. Hay

Parasitic Infections, Raúl M. Cabrera, Rubén T. Guarda., Francis E. Palisson, and Sergio B. González

Tumors of Skin Homing Lymphocytes, Rein Willemze


Immunomodulatory Drugs, Lionel Fry

Therapeutic Manipulation of the Complement System in Dermatology, S. Shafi Asghar

Immunological Strategies to Fight Skin Cancer, Dirk Schadendorf, Annette Paschen, and Stefan Eichmüller

Photo(chemo)therapeutic Modulation of the Skin Immune System, Menno A. de Rie and Jan D. Bos

Biologicals for the Treatment of Immune Mediated Skin Diseases, Menno A. de Rie and Jan D. Bos

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Clinical Medicine
MEDICAL / Dermatology
MEDICAL / Pharmacology