2nd Edition

Sleep Apnea Pathogenesis, Diagnosis and Treatment

Edited By Allan I. Pack Copyright 2011
    570 Pages 187 B/W Illustrations
    by CRC Press

    Sleep apnea is a common chronic condition affecting millions of people. Written by a multidisciplinary team including sleep medicine specialists, pulmonologists, scientists, psychiatrists, otorhinolaryngologists, and more, this text provides essential scientific and clinical information for those treating and researching the condition.

    Since the previous edition published, sleep medicine has become a fully formed medical speciality. This second edition has been expanded to contain more clinically relevant information regarding diagnosis and treatment, and includes:

    • New developments regarding the cardiovascular effects of sleep apnea
    • New developments regarding the role of sleep apnea in insulin resistance
    • Developing research on intermittent hypoxia in the disorder
    • Latest pharmacotherapeutic trials, addressed in the last chapter

    Organized into sections and subsections to make the book easier for the reader to use, this essential text also examines sleep apnea in special populations, such as children, older adults or pregnant women, and takes into account gender differences in the disorder.

    Pathogenesis of obstructive sleep apnea: Insights from upper airway imaging studies, Murtuza M. Ahmed and Richard J. Schwab
    Biomechanics of the upper airway during sleep, Philip L. Smith, Jason P. Kirkness, Susheel Patil, Hartmut Schneider, and Alan R. Schwartz
    Neural mechanisms
    Sleep-induced breathing instability, Ailiang Xie, Curtis A. Smith, and Jerome A. Dempsey
    Mechanisms of upper airway hypotonia, Leszek Kubin and Richard O. Davies
    Autonomic consequences of arousal from sleep and neural mechanisms of arousal, Richard L. Horner

    Studies in humans
    Airway reflexes: Changes with sleep, David P. White
    Gender differences in sleep-disordered breathing, M. Safwan Badr and Jason H. Mateika

    Mechanisms of sleepiness in obstructive sleep apnea, Mark S. Aloia and J. Todd Arnedt
    Neuroimaging studies in obstructive sleep apnea, Liat Ayalon and Sean P. A. Drummond
    Biomarkers and obstructive sleep apnea, Erna Sif Arnardottir, Bernie Sunwoo, and Allan I. Pack
    Cardiovascular consequences

    Obstructive sleep apnea and hypertension: Interactions and clinical implications, Suraj Kapa, Apoor S. Gami, and Virend K. Somers
    Other cardiovascular consequences of sleep apnea, Julio A. Chirinos, Frederick F. Samaha, and Mark H. Sanders
    Neuroendocrine aspects of sleep apnea, Brendon J. Yee, Peter Y. Liu, Craig Phillips, and Ronald R. Grunstein
    Obstructive sleep apnea and glucose metabolism, Jan Polak, Brock A. Beamer, and Naresh M. Punjabi
    Intermittent hypoxia
    Intermittent hypoxia and neurocognitive function, David Gozal, Leila Kheirandish-Gozal, Yang Wang, and Shelley X. L. Zhang
    Obstructive sleep apnea: Mechanisms of intermittent hypoxemia neural injury, Sigrid C. Veasey
    Diagnosis of sleep apnea
    Screening for sleep apnea, Indira Gurubhagavatula
    Alternative strategies for diagnosis of patients with obstructive sleep apnea, Samuel T. Kuna

    Sleep apnea in specialized groups
    Obstructive sleep apnea: Children versus adults, Eliot S. Katz and Carole L. Marcus
    Sleep apnea in older adults, Nalaka S. Gooneratne
    Obstructive sleep apnea in pregnancy and menopause, Grace W. Pien
    Treatment of sleep apnea
    Adherence to CPAP treatment and functional status in adult obstructive sleep apnea, Terri E. Weaver, Judith Reishtein, and Amy M. Sawyer
    CPAP therapy: Results of randomized controlled trials in obstructive sleep apnea, Sophie D. West and John R. Stradling
    Oral appliance therapy for snoring and sleep apnea, Peter A. Cistulli and Ali M. Darendeliler
    Upper airway surgery for obstructive sleep apnea, Edward M. Weaver and Andrew N. Goldberg|
    Pharmacotherapeutic trials for sleep-disordered breathing, Jan Hedner, Ludger Grote, and Ding Zou

    Index 551


    Allan I. Pack