One of the first such volumes in this field, Sleep Disorders: Diagnosis and Therapeutics explores sleep pharmacology and therapeutics. Leading researchers in the area of experimental and clinical and psychopharmacology critically assess the progress in their specialist fields. The book is suitable as an introduction for clinicians and researchers who are new to sleep pharmacology and outlines the wider range of therapeutic options currently available to them. For seasoned clinicians, the book will assist in selecting the most appropriate methodologies and treatment options designed to circumvent the problems in combating sleep disorders.
1. Classification of Sleep Disorders 2. Sleep Loss and Sleepiness 3. Approach to the patient with sleep complaint 4. Manifestations of hypersomnia 5. Neuropsychology of Sleep 6. Receptor mechanisms in sleep and wakefulness 7. Transient Insomnia: A Behavioral Sleep Medicine Perspective 8. Chronic insomnia 9. Robound with Hypnotic medication 10. Benzodiazepines: An overview 11. Benzodiazepines: Effects on memory functioning 12. Behavioral therapy, sleep hygiene and psychotherapy 13. Sleep factors 14. The Cytoch P450 enzyme systems: Its relevance to the Pharmacology of sleep 15. Pharmacokinetics: Basic Concepts for dosage regimen considerations 16. Chronopharmacology: Principles and applications in sleep medicine 17. Sleep and Geriatric Psychopharmacology 18. Antihistamines and sleep 19. First generation hypnotics and sedatives 20. GABA-BZD receptors as target for new hypnotics 21. Benzodiazepines: Effects on sleep 22. Indiplon 23. Serotonergic drugs as sleep medications 24. Prostaglandins and sleep/wake regulation 25. Function of endocannabinoids and related compounds in sleep 26. Sleep Medications: When to Prescribe and Rationale for Use 27. Stimulants: Mechanisms and Therapeutic Prospects 28. Zolpidem: its use in the treatment of sleep disorders 29. Eszopiclone: Efficacy and Safety 30. Zaleplon 31. Z-Drugs: Comparative tolerability 32. Rationale for the development of the Z–drugs 33. Metalonin and other indolamines: their involvement in sleep regulation 34. Ramelteon: a Melatonin receptor agonist 35. The rationale for the development of melatonin receptor ligands 36. Schizophrenia, Sleep and Antipsychotic Drugs 37. Interrelationships Between Sleep, Depression and Antidepressant Drugs 38. Effect of antiepileptic medications on sleep architecutre 39. Hormones and sleep 40. Timezone travel, jet lag and sleep disturbances 41. Alcohol, Sleep, Sleep Disorders, and Consequent Daytime Impairment 42. Sleep medication and traffic safety 43. Effect of hypnotic drugs on body balance and standing steadiness 44. Neuropharmacology of Opioids 45. Sleep and Breathing Disorders in Adults 46. Continuous Positive Airway Pressure Therapy 47. Pharmacological Treatment of Obstructive Sleep Apnea 48. Surgical Options in Snoring and Obstructive Sleep Apnea 49. Restless Legs Syndrome: Treatment Options 50. Restless Legs Syndrome: effects on cognitive functioning, memory and psychomotor performance 51. Pharmacological treatment of narcolepsy 52. Modafinil and neuropharmacology of Narcolepsy 53. Narcolepsy: effects on cognitive functioning, memory and psychomotor performance 54. Dreams: Physiology, Pharmacology and Psychology 55. Sleep and Dreaming: Medication effects and side-effects 56. The Subjective Measurement of Excessive Daytime Sleepiness 57. The Multiple Sleep Latency Test and Maintenance of Wakefulness Test: Use and Procedures 58. The OSLER test 59. The Pittsburgh Sleep Quality Index 60. Scoring Rules and General Guidelines for the Pittsburgh Insomnia Rating Scale (PIRS) 61. The Athens Insomnia Scale 62. The Leeds Sleep Evaluation Questionnaire (LSEQ) for psychopharmacology research 63. Sleep Hygiene Practice Scale (SHPS) 64. Cyclic Alternating pattern (CAP) 65. Body Mass Index