Part I – Sleep
1 – Introduction to sleep
2 – Introduction to the neurochemistry and neuroanatomy of sleep
3 – What happens when things go wrong with sleep
Part II – Brain Injury
4 – Introduction to brain injury: the basics
5 – Common neuroanatomical structures that are affected in brain injury
6 – Functional disturbances caused by brain injury
Part III – The combination of clockwise and counterclockwise vicious cycles
7 - Establishing the link between brain injury and sleep disturbance and sleep disturbance and brain injury
8 – Integration of thoughts
9 – Chronic neuroinflammation and waste disposal: the long and the short of it
Part IV – Treatments or promoting virtuous cycles
10 – Some ideas for research and intervention
11 - First foundation
12 – Second Foundation
13 – Third Foundation
14 – Fourth Foundation
Part V – A recapitulation
15 – Final thoughts
Biography
Crawford M. Thomas has been in healthcare and academe for over 30 years. He has designed, implemented, and led inpatient and community acquired brain injury neurorehabilitation services. A skilled Consultant Clinical Neuropsychologist and Neuroscientist, he is the clinical lead of one of the largest community acquired brain injury teams in the UK, working for Cheshire and Wirral Partnership NHS Foundation Trust.
'Dr Thomas successfully weaves together current knowledge and research from the fields of sleep and brain injury with a vast scope that ranges from the relationship of the neuroanatomical and neurochemical foundations through to the lived experience of the individual. The book expertly constructs a deep appreciation of the complexity and interrelatedness of the extensive ecosystem that is sleep and waking as it structures and encompasses all aspects of life. Based on the intricacies of the above, a complete sleep management approach is offered to promote healthy sleep and waking, which makes clear how things might be improved for those who have experienced a brain injury. It is a must read for anyone working in this area.' - Dr Susan Hooper, BSc (Hons), Cert. Ed, MSc, D Couns Psych, Cert. Rehab, Chartered Psychologist, Registered Counselling Psychologist, HCPC
'An extraordinary work, I have learned so much. A few items that stand out in particular include: the disturbing persistence of pro-inflammatory cytokines (and potential risk of neurodegenerative disease) for years post brain injury, the impact of melatonin and sleep deprivation on bone mineral density, the impact of reduced or excess REM on depressive symptoms, including suicidal ideation post TBI, the unsurprisingly complex and beneficial role of Vitamin D, the microbiome and vagus nerve stimulation: all areas of research in inflammatory arthritis. This book offers a thorough review of the neuroscience of sleep and brain injury, together with novel evidence-based interventions to optimise outcomes.' - Dr Jo MacGowan, BSc (Hons), MBBS, FRCP, Consultant Rheumatologist
'This astonishingly well researched book integrates current knowledge from sleep theory and practice and the wider neurosciences to provide a comprehensive framework for understanding sleep disorders and brain injury, and their interaction. It will be an invaluable resource to guide all neuro-rehabilitation clinicians in assessing and treating such problems.' - Lesley Stewart, M.A., M.Phil, Consultant Clinical Neuropsychologist, Chartered Psychologist, HCPC, Full Practitioner Member Division of Neuropsychology
