2nd Edition

Small Animal Cytologic Diagnosis Canine and Feline Disease

Edited By Anne M. Barger, Amy MacNeill Copyright 2025
    552 Pages 1417 Color & 24 B/W Illustrations
    by CRC Press

    This second edition of Small Animal Cytologic Diagnosis presents clinically applicable information about the use of cytology in small animals and indicates when advanced diagnostic testing can be beneficial to diagnose underlying disease processes. It includes more images, additional cases, and a new user-friendly chapter organization.

    The book discusses the pathophysiology of inflammation, cancer biology and comparisons to histology to help readers fully comprehend the cytologic changes that can occur with inflammation and neoplasia. Also covered are some of the limitations and advantages of cytology compared to histopathology, important gross findings (e.g., body cavity effusions), and parasites and the associated diagnostic methods required. Further information is provided on oncogenes, reference values for effusions and bone marrow aspirates, laboratory handling of samples, and how to carry out certain diagnostics. The book:

    • includes chapters written by experts from around the world.
    • provides multiple cytological images for the same sample, providing different views of what may be seen.
    • uses technical language where appropriate but without overcomplicating the information presented: it is very accessible and easy to understand.

    The book includes tissue-specific chapters focusing on diseases of a particular area, always in comparison to normal tissue. Each of these chapters concludes with various cases that include information on signalment, history, pertinent laboratory data, specimen images, final outcome and the underlying pathology causing the cytologic lesions, when possible. With more than 2000 superb illustrations, this comprehensive resource provides ample practical information for students as well as practicing veterinarians.


    About the editors.

    List of contributors.

    1. Sample Acquisition and Preparation - Anne Barger and Laura Garrett
    2. General Principles of inflammation - Amy MacNeill
    3. Cancer Biology - Timothy M. Fan
    4. Cytology of Skin and Subcutaneous Tissue - Indira Pargass and Samantha Schlemmer
    5. Cytology of Lymphoid Tissue - Stefano Comazzi and Amy MacNeill
    6. Cytology of the oral cavity - Melinda Camus
    7. Cytology of the gastrointestinal tract - Elena Gorman
    8. Cytology of the pancreas - Catherine Trumel, Marie-Noëlle Lucas, Catherine Layssol, Fanny Granat, and Nathalie Bourgès-Abella
    9. Cytology of the liver - A Russell Moore
    10. Cytology of the urinary tract - Julie Webb and Ashleigh Newman
    11. Cytology of the male and female reproductive system - Amy MacNeill
    12. Cytology of the musculoskeletal system - Amy Schnelle
    13. Cytology of the respiratory tract - Amelia Goddard                  
    14. Cytology of the central nervous system - Mike Rosser and Chandler Carter
    15. Cytology of Effusions - Ilse Schwendenwein
    16. Cytology of the endocrine system - Sara Connolly
    17. Cytology of the eye and adnexa - Anne Barger and Samantha Lee
    18. Cytology of the ear - Cheryl Moller, Jennifer Neel, and Marcie Murphy
    19. Cytology of bone marrow - Emmiline Tan and Dorothee Bienzle



    Dr. Anne Barger graduated from the University of Illinois in 1996 and after graduation, went on to a clinical pathology residency program at North Carolina State University. After completion of her residency, she worked for Antech Diagnostics for two years, before accepting a faculty position at the University of Illinois in 2002. Her research interests include clinical cytology and immunocytochemistry as it pertains to diagnosis of canine and feline neoplasia. Currenty, she is the deparment head of Veterinary Clinical Medicine at the University of Illinois.

    Dr. Amy MacNeill graduated from the University of Florida College of Veterinary Medicine in 1998. Following a year in private practice, she returned to the University of Florida to complete clinical pathology residency and a PhD in virology and immunology.  In 2005, she joined the faculty at the University of Illinois.  In 2014, she accepted a clinical pathology faculty position at Colorado State University.  Her research interests include isolation and characterization of canine and feline tumor cells and the study of poxviruses as anticancer agents.