1st Edition

Solid-Phase Extraction
Principles, Techniques, and Applications



ISBN 9780824700218
Published March 15, 2000 by CRC Press
528 Pages

USD $220.00

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Book Description

Demonstrating the relationship of the basic theory of solid-phase extraction (SPE) to chromatography, this comprehensive reference illustrates how SPE techniques significantly contribute to the preparation of samples for a wide variety of analytical techniques. It provides step-by-step details on the applications of SPE to environmental matrices, broad-spectrum drug screening, veterinary drug abuse, pharmaceutical drug development, biological samples, and high-throughput screening. Written by world-renowned experts in the field, the book contains helpful reference charts, tables of solvent properties, selectivities, molecular acid/base properties, and more.

Table of Contents

Introduction to Solid-Phase Extraction, N.J.K. Simpson and M.J.M. Wells
SPE Sorbents and Formats, J.J. Pesek and M.T. Matyska
The Sample Matrix and Its Influence on Method Development, N.J. K. Simpson and P.M. Wynne
Handling Large Volume Samples: Applications of SPE to Environmental Matrices, M.J.M. Wells
SPE Technology 150; Principles and Practical Consequences, M. Henry
Theory Meets Practice, C.F. Poole and S.K. Poole
Secondary Interactions and Mixed-mode Extraction, B. Law
Solid-Phase Extraction for Broad-Spectrum Drug Screening in Toxicological Analysis, R.A. de Zeeuw
The Application of SPE to Veterinary Drug Abuse, P.M. Wynne
Solid Phase Extraction of Biological Samples, S.H. Ingwersen
Solid Phase Extraction Mediated by Covalent Bonding: Applications of Immobilized Phenylboronic Acid, I. D. Wilson and P. Martin
Immuno-Affinity Extraction, D. Stevenson, B.A.A. Rashid, and S.J. Shahtaheri
Matrix Solid Phase Dispersion (MSPD), S.A. Barker
Automation of Solid Phase Extraction, L. Dordan
Integration of SPE with the Analytical Technique, Part I - Liquid Chromatography, N.J.K. Simpson
Integration of SPE with the Analytical Technique, Part II, N.J.K. Simpson
Concluding Thoughts - New Directions for SPE, N.J. K. Simpson

Appendix 1: A Summary of Common Matrix Properties and Components, N.J.K. Simpson
Appendix 2: A Comparison Between Solid Phase Extraction and Other Sample Processing Techniques, N.J.K. Simpson
Appendix 3: Ion Exchange Extraction, N.J.K. Simpson
Appendix 4: A Summary of Current Suppliers of SPE Automation Equipment, N.J.K. Simpson

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