1st Edition

Statistical Methods in Epilepsy

Edited By Sharon Chiang, Vikram Rao, Marina Vannucci Copyright 2024
418 Pages 95 B/W Illustrations
by Chapman & Hall

418 Pages 95 B/W Illustrations
by Chapman & Hall

Epilepsy research promises new treatments and insights into brain function, but statistics and machine learning are paramount for extracting meaning from data and enabling discovery. Statistical Methods in Epilepsy provides a comprehensive introduction to statistical methods used in epilepsy research. Written in a clear, accessible style by leading authorities, this textbook demystifies... Read more

1. Coding Basics
Emilian R. Vankov, Rob M. Sylvester and Christfried H. Focke

2. Preprocessing Electrophysiological Data: EEG, iEEG and MEG Data
Kristin K. Sellers, Joline M. Fan, Leighton B.N. Hinkley and Heidi E. Kirsch

3. Acquisition and Preprocessing of Neuroimaging MRI Data
Hsiang J. Yeh

4. Hypothesis Testing and Correction for Multiple Testing
Doug Speed

5.  Introduction to Linear, Generalized Linear and Mixed-Effects Models
Omar Vazquez, Xiangmin Xu and Zhaoxia Yu

6. Survival Analysis
Fei Jiang and Elan Guterman

7. Graph and Network Control Theoretic Frameworks
Ankit N. Khambhati and Sharon Chiang

8. Time-Series Analysis
Sharon Chiang, John Zito, Vikram R. Rao, and Marina Vannucci

9. Spectral Analysis of Electrophysiological Data
Hernando Ombao and Marco Antonio Pinto-Orellana

10. Spatial Modeling of Imaging and Electrophysiological Data
Rongke Lyu, Michele Guindani and Marina Vannucci

11. Unsupervised Learning
Giuseppe Vinci

12. Supervised Learning
Emilian R. Vankov and Kais Gadhoumi

13. Natural Language Processing
Christfried H. Focke and Rob M. Sylvester

14. Prospective Observational Study Design and Analysis
Carrie Brown, Kimford J. Meador, Page Pennell, and Abigail G. Matthews

15. Pharmacokinetic and Pharmacodynamic Modeling
Ashwin Karanam, Yuhan Long and Angela Birnbaum

16. Randomized Clinical Trial Analysis
Joseph E. Sullivan and Michael Lock

Biography

Sharon Chiang is a research fellow in the Department of Physiology and instructor in the Epilepsy Division in the Department of Neurology at the University of California, San Francisco, USA. Her research focuses on development of methods for state-space models in the estimation of seizure risk and neural mechanisms of memory consolidation in epilepsy.

Vikram R. Rao is Associate Professor of Clinical Neurology, Ernest Gallo Distinguished Professor, and Chief of the Epilepsy Division in the Department of Neurology at the University of California, San Francisco, USA. His clinical and research interests involve applications of neurostimulation devices for drug-resistant epilepsy, neuropsychiatric disorders, and seizure forecasting.

Marina Vannucci is Noah Harding Professor of Statistics at Rice University, Houston, TX, USA, and also holds an Adjunct Professor appointment at the MD Anderson Cancer Center, Houston, TX, USA. Her research is focused on the development of Bayesian statistical methodologies for application in genomics, neuroscience and neuroimaging.