Acknowledgements
PART I. AN INTRODUCTION TO STEM CELLS
1. The essential principles of stem cell science
2. Stem cell identification, isolation, and characterization
PART II. STEM CELL POTENCY AND CONTROL
3. Embryonic stem cells, cloning, and pluripotency
4. Controlling stem cells: Receipt and interpretation of external cues
5. Cell plasticity, reprogramming, and induced pluripotent stem cells
6. The stem cell niche
PART III. STEM CELLS ACROSS THE ANIMAL AND PLANT KINGDOMS
7. Regeneration in animals: The evolution of stem cells
8. Plant stem cells
PART IV. STEM CELLS IN SPECIALIZED ADULT ANIMAL TISSUES
9. Hematopoietic stem cells
10. Musculo-skeletal and dental stem cells in mammals
11. Stem cells in endoderm-derived organs
12. Stem cells underpinning the generation of germ cells
13. Stem cells in the cardiovascular system
14. Stem cells in the nervous and sensory systems
15. Stem cells in the skin, its appendages, and other epithelial tissues
16. Atypical stem cells that enable and modulate immune system function
PART V. BIOMEDICAL AND ECONOMIC APPLICATIONS OF STEM CELLS
17. Stem cells in biomedicine: Disease modeling and tissue repair
18. Stem cells in biomedicine: Stem cells in aging and cancer
19. Stem cell applications in domesticated and wild animals and in horticulture
20. Stem cells and society: A philosophical, ethical, and economical view
Glossary
Index
Biography
Prof Jon Frampton and Dr Mary Clarke are stem cell biologists in the Institute of Cancer and Genomic Sciences at the University of Birmingham. Their main research involves hematopoietic stem cells, trying to understand how their normal behaviour is affected by disease and aging.
