This book explores the potentiel of stem cells for ameliorating the quality of life of patients with neurological and neurodegenerative diseases. It discusses results of pre-clinical investigations and case studies on the effects of stem cell transplantation on cell death, to promote/stimulate neuroprotection after brain and spinal cord injury through trophic support, cell replacement and remyelination. It covers the maintenance of the balance between stem cells and their progenitors within their niche, both under normal and degenerative processes, ischemic stroke, multiple sclerosis, and brain tumor.
Table of Contents
Stem Cells as a Source for Cell Therapy in Parkinson's Disease
J.Ganz, Nirit Lev, and D.lOffen
The use of stem cells in treating Huntington’s disease: state of research and prospects for future treatments
KD.Fink, AT.Crane, J. Rossignol, L. Lescaudron, andGL. Dunbar
Stem Cell Transplantation Strategies After Spinal Cord Injury
JT Wilcox, R. Vawda , and MG Fehlings
Role of endogenous neural precursor cells in Multiple Sclerosis
G. Spigoni, V. Tepavcevic, B. Nait-Oumesmar, and A. Baron Van-Evercooren
Stem cells and Alzheimer’s disease
P.Brachet, and V.Bonnamain
Cell Therapies for Ischemic Stroke
LL. Stone, WC. Low, and A. Grande
Immune response to intracerebral transplantation: particular properties of stem cells
E. Mathieu , V. BonnamainP. Naveilhan, and I. Neveu
Glioma stem cells: the brain behind the tumor?
L. Oliver, C. Pecqueur, M. Moufouace , and FM. Vallette
The future of induced pluripotent stem cells in brain regenerative medicine
J-M. Ramirez, B. Qiang , and J. De Vos
Lescaudron, Laurent; Rossignol, Julien; Dunbar, Gary L.