1st Edition

Structural Glycobiology

Edited By Elizabeth Yuriev, Paul A. Ramsland Copyright 2013

    Structural Glycobiology covers the experimental, theoretical, and alternative technologies used in the study of the structural basis for the diverse biological roles of carbohydrates. The book overviews the application of specialized technologies to the study of carbohydrates in biology, reviews relevant and current research in the field, and is il

    Experimental Techniques to Determine Three-Dimensional Structures: Crystallography and Small-Angle Scattering of Carbohydrate-Protein Complexes and Glycoproteins. Nuclear Magnetic Resonance Studies of Carbohydrate-Protein Interactions. Electron Cryomicroscopy of Large Glycoprotein Assemblies. Theoretical/Modeling Techniques to Predict Three-Dimensional Structures: Protein-Carbohydrate Interactions: Computational Aspects. Docking of Carbohydrates into Protein Binding Sites. Alternative Approaches for Yielding Detailed Structural Information: Mass Spectrometry for Glycomics Analysis of N- and O-Linked Glycoproteins. Glycan-Based Arrays for Determining Specificity of Carbohydrate-Binding Proteins. Carbohydrates in Medicine: Structural Glycobiology: Applications in Cancer Research. Structural Glycobiology: Applications in Organ Transplantation. Structural Glycobiology: Applications in Viral Infection. Developing Drugs from Sugars Current State of Glycosaminoglycan-Derived Therapeutics.

    Biography

    Elizabeth Yuriev is with the Monash Institute for Pharmaceutical Sciences at Monash University, Australia. Paul A. Ramsland is with the Centre for Immunology at the Burnet Institute in Melbourne, Australia.