1st Edition

Supramolecular Design for Biological Applications

Edited By Nobuhiko Yui Copyright 2002
    424 Pages 209 B/W Illustrations
    by CRC Press

    Supramolecular chemistry is the outburst topic of the next generation of science. While the majority of biomedical research efforts to date have centered on utilizing well-known polymeric materials, the recent progress in supramolecular chemistry has introduced a fascinating new field of macromolecular architecture.

    Supramolecular Design for Biological Applications focuses on modulating, altering, and mimicking biological functions with a new family of molecular assemblies. The authors provide innovative ideas and concepts for developing novel biomaterials that could be applied in diagnosis, drug carrier operations, and environmental protection. This reference is comprehensive, presenting principles, applications, recent advances, and future directions. Each chapter includes clear and informative illustrations of molecular architectures. The writing is scientific but allows for easy comprehension of the differences in molecular interactions, dimensions, and supramolecular architecture.

    Supramolecular Design for Biological Applications will advance the understanding of supramolecular-structured biomaterials and associated issues regarding biological functions. By explaining recent trends and molecular interactions, this book will enable you to initiate new research for nano-scale science and technology in the 21st century.

    General Introduction, Yui/Kishida/Yamaoka/Ohya
    Basic Strategy for Supermolecular Architectures
    Hydrophobic Effects, Akiyoshi
    Hydrogen Bonds, Ohya
    Electrostatic Interaction, Maruyama
    Physical Adsorption for Supermolecular Design, Serizawa
    Gel and Interpenetrating Polymer Networks, Miyata
    Interlocked Molecules, Yui/Ikeda
    Biological Application of Supramolecular Architectures
    Biodegradable Polymers, Yui/Ooya
    Stimuli-Responsive Polymers and Gels, Miyata
    Modulated Drug Delivery, Qui/Park
    Drug Targeted with Polymeric Micelle Drug Carriers, Yokoyama
    Gene Delivery, Yamaoka
    Sensing and Diagnosis, Maeda
    Organic/Inorganic Supramolecular Assembly, Kishida
    Biometric Function, Ariga
    Supramoleculars Surfaces, Ishihara
    Supramoleculars Approaches for Cellular Modulation, Fujimoto
    Future Aspects - Supramolecular Architectures Towards Biological Applications
    Future Aspects - Supramolecular Architectures Towards Biological Applications, Kimizula


    Nobuhiko Yui

    "…the contributions have a uniform style and fit together very well. The diligence of the editor is obvious. …all the chapters have very balanced references, citing the important historic contributions to polymer chemistry and networks, and are written in a tutorial style …an excellent introduction to new students seeking to make a career in biomaterials and bioartificial organs, while updating the expert."
    - David Hunkeler, AQUA+TECH Specialties, Switzerland, in Polymer News

    " … it represents a timely subject, supramolecular assemblies are an exploding area of research with many functional applications. The chapters cover a broad spectrum of topics and include well-respected researchers. I feel that this book would be an excellent addition to the supramolecular literature and a valued resource."
    - Allison A. Campbell, Ph.D., Deputy Director, WR Wiley Environmental Molecular Sciences Laboratory, Richland, Washington, USA