1st Edition
Syncope From Etiopathogenesis to New Therapeutic Options
Syncope is a common condition related to transient loss of consciousness due to global cerebral hypoperfusion and caused by a variety of aetiologies. Although it is self-limited, and usually benign, syncope can be the harbinger of life-threatening heart rhythm problems due to cardiac conditions. A multidisciplinary approach is practical for its evaluation and treatment, requiring the expertise of cardiologists, neurologists, emergency medicine specialists, and other clinicians. This book provides a detailed review of etiopathogenesis and a state-of the art update on therapeutic options offering recommendations based on the guidelines and experience of experts while discussing procedures and tests with their indications, methodology, interpretation, and limitations.
Key Features: 1. Discusses new diagnostic tools, and therapeutic modalities, with supportive videos in each chapter. 2. Provides up-to-date recommendations regarding the indications for and appropriate interpretation of non-invasive and invasive cardiac testing, for cardiologists and internists. 3. Places particular emphasis on diagnosing and treating reflex and arrhythmic syncope.
Chapter 1: Syncope: Definition, Terminology and Classification
John A. Paydar, Liane A. Arcinas, Carlos A. Morillo, Robert S Sheldon, and Satish R Raj
Chapter 2. Epidemiology and Economics of Syncope
Dana Shiffer and Raffaello Furlan
Chapter 3. Etiopathogenesis of Syncope
Lina E. Lombo, Juan Camilo Guzmán
Chapter 4. Initial Evaluation and Risk Stratification in Syncope
Robert Sheldon, Liane Arcinas, Frederik de Lange, and Roopinder Sandhu
Chapter 5. Diagnostic Tests in Syncope
Chapter 5A. Tilt-table testing, Autonomic Tests and Electrophysiological Study
Wayne O Adkisson, and David G Benditt
Chapter 5B. ECG, Prolonged Ambulatory Monitoring, and Exercise Stress Testing
Matthew T. Bennett, and Andrew D Krahn
Chapter 6. Reflex Syncope
6A. Vasovagal Syncope
William H. Parker, Mark W. Chapleau, and Brian Olshansky
6B. Other Causes of Reflex syncope
Piotr Kulakowski
Chapter 7. Adenosine Sensitive Syncope: Diagnosis & Management
Régis Guieu, Michele Brignole, and Jean Claude Deharo
Chapter 8. Disorders of Orthostatic Intolerance: Orthostatic Hypotension and Postural Orthostatic Tachycardia Syndrome
Jacquie R. Baker, and Satish R. Raj
Chapter 9. Cardiac Syncope
Angel Moya-Mitjans and Jaume Francisco-Pascual
Chapter 10. Syncope in children
Khalil Kanjwal, Wasim Rashid, and Blair P. Grubb
Chapter 11. Pseudosyncope and ictal syncope: Diagnosis & Management
Leonardo Calò, Marco Rebecchi, Pietro Desimone, Doménico Giamundo, Ermenegildo De Ruvo, and Antonella Sette
Chapter 12. Other neurological conditions (Sleep disorders, autonomic failure, and structural brain lesions)
Ann-Kathrin Kahle, Katharina Scherschel, Fares-Alexander Alken, and Christian Meyer
Chapter 13. Management of Reflex Syncope
13A. Non-pharmacological and Pharmacological Management of Reflex Syncope
Giulia Rivasi, and Artur Fedorowski
13B. Cardioneuroablation
Tolga Aksu, Jeanne M. Du-Fay-de-Lavallaz, and Asad Khan
13C. Cardiac Pacing in Reflex Syncope
Michael Liu, Dan Sorajja, and Win-Kuang Shen
Chapter 14. The Legal Aspects of Syncope
Frederik J de Lange, and Robert S Sheldon
Chapter 15. Syncope & Falls in Older Adults
Desmond O’ Donnell, and Rose Anne Kenny
Biography
Tolga Aksu, MD, FESC, FEHRA
Dr, Aksu is a Professor of Cardiology. Currently a member of the Department of Cardiology and Director of Clinical Electrophysiology at the Yeditepe University Hospital in Turkey. Dr. Aksu is clinically interested in invasive electrophysiology, device implantation and catheter ablation therapies. Special interest areas include Atrial fibrillation and cardioneuroablation, and has been a pioneer and advocate in this field. Dr. Aksu has published more than 130 international scientific publications. He is an Associate Editor of Journal of Electrocardiology and SoMe Editor of JICE. He is also a member of the Editorial Board of World Journal of Cardiology, Medicine Journal, Journal of Atrial Fibrillation, and Journal of Cardiac Arrhythmias.
Carlos A. Morillo, MD, FRCPC, FACC, FHRS, FESC
Prof Carlos A. Morillo is a cardiac electrophysiologist, and served as the Chief Division of Cardiology (2015-2022) at the Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada, and currently on an academic sabbatical leave at the Molecular and Novel Arrhythmia Mechanisms group at the Centro Nacional de Investigaciones Cardiovaculares (CNIC) in Madrid, Spain. He has been involved in syncope research since 1986, and has extensively investigated the mechanisms of neurally mediated syncope and participated and led several landmark clinical trials related with the diagnosis and management of vasovagal syncope including the VPS, POST and SPAIN trials. Prof Morillo has published over 350 peered reviewed articles and has also participated in several syncope guidelines from the ESC, ACC, AHA, HRS and Canadian Society of Cardiology. Prof Morillo's key research areas are related to the development of clinical trials in the area syncope, cardiac arrhythmias, AF ablation, screening and detection of AF in varied populations, and treatment of Chagas Disease.
