Systematic Approach to Evaluation of Mouse Mutations  book cover
1st Edition

Systematic Approach to Evaluation of Mouse Mutations

Edited By

John P. Sundberg

ISBN 9780367399580
Published October 17, 2019 by CRC Press
216 Pages

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Book Description

Experts from The Jackson Laboratory and around the world provide practical advice on everything from how to establish a colony to where to go for specific mutations. Systematic Approach to Evaluation of Mouse Mutations includes information on medical photography, grafting procedures, how to map the genes and evaluate the special biological characteristics of the mice.

Table of Contents

Mouse Colony Establishment-Determining the Genetic Basis of a New Trait-Xavier Montagutelli Computerized Colony Record Keeping-Medical Record Keeping for Project Analysis-Necropsy Methods for Laboratory Mice. Biological Characterization of a New Mutation- Photography of Mutant Laboratory Mice-Comparative Pathology and Animal Model Development-Kinetics and Morphometrics-Ultrastructural Evaluation of Mouse Mutations-Immunohistochemical and Immunofluoresence Methods-Radiolabeled cRNA and In Situ Hybridization-In Situ Hybridization with Non-Radiolabeled Probes-Repositories of Mouse Mutations and Inbred, Congenic and Recombitant Inbred Strains

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John P. Sundberg, Dawnalyn Boggess