3rd Edition

Systematic Reviews to Support Evidence-Based Medicine How to appraise, conduct and publish reviews

By Khalid Saeed Khan, Javier Zamora Copyright 2023
    238 Pages
    by CRC Press

    238 Pages
    by CRC Press

    Authoritative, clear and concise, this highly acclaimed book continues to be an essential text for all medical, surgical and allied health professionals who are seeking a quick and respected guide to systematically reviewing the literature. The third edition features a new chapter on 'Publishing systematic reviews’ and numerous new case studies covering the latest developments in the field, including umbrella reviews, reviews of test accuracy, qualitative evidence and prognostic studies, and practice guidelines.

    The highly experienced authors, who have each contributed to numerous systematic reviews that have helped form policy and practice, ensure that this practical text, which avoids technical jargon, continues to be the reference of choice for all health professionals undertaking literature reviews, including those specializing in epidemiology and public health.


    About the authors


    Additional contributors



    Steps of a systematic review

    Step 1: Framing questions for a review

    Step 2: Identifying relevant literature

    Step 3: Assessing the quality of the literature

    Step 4: Summarizing the evidence

    Step 5: Interpreting the findings

    Case studies

    Case study 1: Review of systematic reviews

    Case study 2: Reviewing the safety of a public health intervention

    Case study 3: Reviewing the effectiveness of therapy

    Case study 4: Reviewing the accuracy of a test

    Case study 5: Reviewing qualitative evidence to evaluate patient experience

    Case study 6: Reviewing the effects of educational interventions

    Case study 7: To use or not to use a therapy? Incorporating evidence on harmful outcomes

    Case study 8: Review of clinical practice guidelines

    Case study 9: Systematic reviews to assess a prognostic factor

    Case study 10: Publishing systematic reviews: Tips and tricks for convincing journal editors and peer reviewers


    Suggested reading



    Khalid S. Khan is Beatriz Galindo Distinguished Investigator at the University of Granada, Spain and has been Sims Black Fellow of the UK Royal College of Obstetricians and Gynaecologists, Spinoza Professor at the University of Amsterdam, the Netherlands, Fellow of the Pakistani College of Physicians and Surgeons, and Fellow of the UK Higher Education Academy.

    Javier Zamora is Head of the Clinical Biostatistics Unit at Ramon y Cajal University Hospital and the Director of the Clinical Epidemiology at the Ramon y Cajal Biomedical Research Institute (IRYCIS), Madrid Spain and is Professor of Biostatistics in Maternal and Perinatal Health at the University of Birmingham, UK.