1st Edition

Systems-Level Modelling of Microbial Communities Theory and Practice

By Aarthi Ravikrishnan, Karthik Raman Copyright 2019
    100 Pages 5 B/W Illustrations
    by CRC Press

    100 Pages 5 B/W Illustrations
    by CRC Press

    Systems-Level Modelling of Microbial Communities: Theory and Practice introduces various aspects of modelling microbial communities and presents a detailed overview of the computational methods which have been developed in this area. This book is aimed at researchers in the field of computational/systems biology as well as biologists/experimentalists studying microbial communities, who are keen on embracing the concepts of computational modelling. The primary focus of this book is on methods for modelling interactions between micro-organisms in a community, with special emphasis on constraint-based and network-based modelling techniques. A brief overview of population- and agent-based modelling is also presented. Lastly, it covers the experimental methods to understand microbial communities, and provides an outlook on how the field may evolve in the coming years.

    Chapter 1. Introduction to microbial communities

    Chapter 2. Networkbased modelling of microbial communities

    Chapter 3. Populationand agentbased modelling of microbial communities

    Chapter 4. Constraintbased modelling of microbial communities

    Chapter 5. Experimental techniques to understand

    Chapter 6. Outlook


    Aarthi Ravikrishnan is a senior graduate student at the Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras. She works on integrating computational and experimental approaches to understand microbial interactions in communities.

    Karthik Raman is an Associate Professor at the Bhupat and Jyoti Mehta School of Biosciences, IIT Madras. He also coordinates the Initiative for Biological Systems Engineering and is a core member of the Robert Bosch Centre for Data Science and Artificial Intelligence at IIT Madras. His group works on computational approaches to understand and manipulate biological networks, with a focus on applications in metabolic engineering.

    "The study of microbiomes and microbial communities has grown exponentially in recent years due to the amazing implications they have for things we, humans, care a lot about, such as health or the environment. This book, Systems-level modelling of microbial communities: theory and practice, brilliantly covers the latest advances in experimental and modelling techniques, which makes it essential for everyone from newcomers to the field to reputed experts."

    -Rodrigo Ledesma-Amaro, Imperial College London