6th Edition

Textbook of Assisted Reproductive Techniques Two Volume Set

    886 Pages 209 Color & 108 B/W Illustrations
    by CRC Press

    Established as a definitive reference for the IVF laboratory and clinic, the sixth edition has been extensively revised, with the addition of several important new contributions on clinical topics, including Artificial Intelligence, gene editing, disaster management, freeze-all cycles, immunology, and transgender considerations. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts. *Gives both laboratory staff and clinicians a comprehensive resource for problems arising in Reproductive Medicine *Draws on international expertise for practice and guidelines *Presents a new edition of the pre-eminent reference text in laboratory and clinical aspects of Reproductive Medicine

    Volume 1: Laboratory perspectives


    1. Updated guidelines for setting up an assisted reproduction technology laboratory - Jacques Cohen, Mina Alikani, and Antonia Gilligan. 2. Quality control maintaining stability in the laboratory - Ronny Janssens, Neelke De Munck, and Johan Guns. 3. KPIs for the IVF laboratory - Alison Campbell. 4. QC in the Clouds-Digitizing quality control - Giles Anthony Palmer. 5. The assisted reproduction technology laboratory: Current standards - Cecilia Sjöblom. 6. Evaluation of sperm - Chelsey A. Leisinger, Kaylen M. Silverberg, and Matthew D. Vermilyea. 7. Sperm preparation techniques and advanced sperm selection for intracytoplasmic sperm injection - Sinan Ozkavukcu, George Hughes, and Christopher L R Barratt. 8. Sperm chromatin assessment - Ashok Agarwal and Rakesh Sharma. 9. Oocyte retrieval and selection - Laura Rienzi, Rosaria Gentile, Federica Innocenti, Danilo Cimadomo, Alberto Vaiarelli, and Filippo Maria Ubaldi. 10. Preparation and evaluation of oocytes for intracytoplasmic sperm injection - Irit Granot and Nava Dekel. 11. Use of IVM in a clinical setting: What is its role in ART? - Tuong M Ho and Lan N Vuong. 12. Intracytoplasmic sperm injection: Technical aspects - Sydney Souness, Philip Xie, Stephanie Cheung, Olena M. Kocur, Carina Sung, Zev Rosenwaks, and Gianpiero D. Palermo. 13. Human embryo biopsy procedures - Maurizio Poli, Ludovica Picchetta, and Antonio Capalbo. 14. Analysis of fertilization - Thomas Ebner. 15. Culture Systems for the Human Embryo - David K. Gardner. 16. Embryo selection through the analysis of morphology and physiology - Denny Sakkas and David K. Gardner. 17. Evaluation of embryo quality: Time-lapse imaging to assess embryo morphokinesis - Akhil Garg, María Ángeles Valera, and Marcos Meseguer. 18. Artificial Intelligence (AI) - Daniella Gilboa. 19. AI in Gamete and Embryo Selection - Peter He, Neringa Karpaviciute, Cristina Hickman, and Nikica Zaninovic. 20. Demystifying vitrification - Debra A. Gook and Kelly Lewis. 21. Vitrification of the Human Oocyte - Masashige Kuwayama. 22. The human embryo: vitrification - Zsolt Peter Nagy and Ching-Chien Chang. 23. Managing an oocyte bank - Ana Cobo, Pilar Alamá, José María de los Santos, María José de los Santos, and José Remohí. 24. Severe male factor infertility: Genetic consequences and recommendations for genetic testing - Katrien Stouffs. 25. Preimplantation genetic testing for aneuploidy to improve clinical outcomes - Jenna S. Hynes, Eric J. Forman, and Alan H. Handyside. 26. Diagnosis of endometrial receptivity, embryo–endometrial dialog, and endometrial microbiome - Maria Ruiz-Alonso, Inmaculada Moreno, Felip Vilella and Carlos Simon. 27. Artificial Gametes: Oocytes - Evelyn E Telfer and Yvonne L Odey. 28. How microfluidics and microfabrication will improve diagnosis and treatment in Human ART - Dale M. Goss, Steven A. Vasilescu, Majid E. Warkiani, Jeremy G. Thompson and David K. Gardner. 29. Genome Editing in Human Reproduction - Helen C.O’Neill. 30. Designing Disaster Plans for IVF Laboratories - Kimball O. Pomeroy and Michael L. Reed. 31. Early human embryo development revealed by static imaging - Yanina D. Alvarez and Melanie D. White


    Volume 2: Clinical perspectives


    32. Quality management in reproductive medicine - Michael Alper. 33. The use of digitalisation and precision medicine in the IVF clinic - Fleur Cattrall. 34. Lifestyle, periconception, and fertility - Jessica A. Grieger, Lisa J. Moran, Sarah A. Robertson, Rui Wang, and Robert J. Norman. 35. Human Reproduction across the Life Course and the Total Environment - Leah Martin, Yu Zhang, Irene Souter, and Carmen Messerlian. 36. Indications for in vitro fertilization treatment - Julie Labrosse and Michaël Grynberg. 37. Initial investigation of the infertile couple - Ranit Hizkiyahu, William Buckett, and Togas Tulandi. 38. Prognostic testing for ovarian reserve - Simone L. Broer, Charlotte H.E. Weimar, Bart C.J.M. Fauser, and Frank J. Brokemans. 39. Drugs used for ovarian stimulation: Clomiphene citrate, aromatase inhibitors, metformin, gonadotropins, gonadotropin releasing hormone analogs, and gonadotropins - Colin Howles and Zeev Shoham. 40. The role of follicle-stimulating hormone and luteinizing hormone in ovarian stimulation: Current concepts – Ernesto Bosch, Elena Labarta, and Elkin Munoz. 41. Endocrine characteristics of assisted reproductive technology cycles - Bulent Urman, Baris Ata, and Hakan Yarali. 42. The use of gonadotropin-releasing hormone agonists and the efficiency of in vitro fertilization - Pasquale Patrizio, Sanaz Ghazal, Judith A.F. Huirne, and Roel Schats. 43. Gonadotropin-releasing hormone antagonists in ovarian stimulation for in vitro fertilization - Efstratios M. Kolibianakis, Pinelopi G. Ioannidou, Julia K. Bosdou, Georg Griesinger, and Basil C. Tarlatzis. 44. GnRH Agonist Triggering - Katherine Koniares, Leah Kaye, Claudio Benadiva, and Lawrence Engmann. 45. Segmentation of in vitro fertilization cycles - Ana Raquel Neves and Nikolaos P Polyzos. 46. Controlled ovarian stimulation for freeze-all cycles - Yossi Mizrachi and Ariel Weissman. 47. Immunology in ART - Isabel Cuadrado Torroglosa, Diana Alecsandru, and Juan A Garcia-Velasco. 48. Monitoring of stimulated cycles in assisted reproduction - Martina Capuzzo and Antonio La Marca. 49. Home monitoring of ART cycles - Wenjing Zheng, Jan Gerris, Eline Dancet, and Thomas D’Hooghe. 50. Oocyte collection - Andrew Murray and Gab Kovacs. 51. Luteal phase support in assisted reproduction techniques - Cristina Rodríguez-Varela and Elena Labarta. 52. Treatment strategies in assisted reproduction for the poor-responder patient – Ariel Weissman and Colin M. Howles. 53. The Poseidon stratification of ‘Low Prognosis Patients in ART’: Management strategies and outcomes - Sandro C. Esteves, Hakan Yarali, Peter Humaidan, and Carlo Alviggi. 54. Controlled ovarian stimulation for low responder patients - Alberto Vaiarelli, Danilo Cimadomo, Cecilia Rucci, Pasquale Petrone, Carlotta Scarafia, Laura Rienzi, and Filippo Maria Ubaldi. 55. Adjuvants for poor responders - Christos A. Venetis. 56. Innovative therapies in Diminished Ovarian Reserve (DOR) and Primary Ovarian Insuffiency (POI) patients - Francesc Fabregues, Janisse Ferreri, and Marta Mendez. 57. Repeated Implantation Failure - David Reichman, Hey-Joo Kang, and Zev Rosenwaks. 58. Ultrasonography in Assisted Reproduction - Laurel Stadtmauer, Jayapriya Jayakumaran, David Cohen, and Ilan Tur-Kaspa. 59. Sperm recovery techniques: Clinical aspects and laboratory processing - Tournaye Herman, De Munck Neelke, Patricio Donoso Pozo, and Francisco Osorio Martini. 60. Embryo Transfer Technique - Leah Roberts and Jason Franasiak. 61. Cycle regimes for frozen–thawed embryo transfer - Jane Reavey and Tim Child. 62. The role of the anesthesiologist in In Vitro Fertilization - Alexander Ioscovich, Yair Binyamin, and Daniel Shatalin. 63. Endometriosis and ART - Jamie Merkison, Marisa Berger, Christian Huang, Aaron Rosen, and Alan DeCherney. 64. Polycystic ovary syndrome and assisted reproduction - Adam H. Balen. 65. Fertility preservation strategies – Stine Gry Kristensen and Claus Yding Andersen. 66. Uterus transplantation – in transition from experimental to clinical procedure - Mats Brännström, Ghada Hussein, Ali Khatibi, and Pernilla Dahm-Kähler. 67. Viral disease and ART - Carole Gilling-Smith. 68. Fertility options for transgender and nonbinary individuals - Molly B Moravek. 69. Ovarian Hyperstimulation Syndrome - Federica Di Guardo and Christophe Blockeel. 70. Bleeding, severe pelvic infection, and ectopic pregnancy - Raoul Orvieto. 71. Egg and embryo donation – Mark V. Sauer and Haley G. Genovese. 72. Gestational surrogacy - Arieh Raziel. 73. Patient support in the assisted reproduction technology program – Sharon N. Covington and Laura S. Covington. 74. The relationship between stress and In Vitro Fertilization Outcome - Alice D. Domar. 75. Risk and safety management in assisted reproduction technology – Paul Pireta, Dominique De Ziegler, Sean Soketang, Chloe Tran, and Jean-Marc Ayoubi.



    David K. Gardner AM, FAA, DPhil is the Scientific Director of Melbourne IVF, and a Distinguished Professor in the School of BioSciences at the University of Melbourne, Australia.

    Ariel Weissman MD is a Senior Physician at the IVF Unit, Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, and a full Professor of Obstetrics and Gynecology at the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

    Colin M. Howles PhD, FRSM is based at Aries Consulting SARL, Geneva, Switzerland, and is an Honorary Fellow, University of Edinburgh, UK.

    Zeev Shoham MD is a Professor at the Hebrew University, Jerusalem, Israel, a consultant in IVF, and co-founder of IVF-Worldwide.