6th Edition
Textbook of Assisted Reproductive Techniques Volume 1: Laboratory Perspectives
Established as the definitive reference for the IVF clinic, the sixth edition has been extensively revised, with the addition of several important new contributions on laboratory topics, including KPIs for the IVF laboratory, Quality control in the cloud, Artificial Intelligence, AI in gamete and embryo selection, Demystifying vitrification, Microfluidics, Gene editing, Disaster management, and Early human embryo development revealed by static imaging. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.
Preface
Contributors
1. Updated Guidelines for Setting up an Assisted Reproductive Technology Laboratory
Jacques Cohen, Mina Alikani, and Antonia Gilligan
2. Quality Control: Maintaining Stability in the Laboratory
Ronny Janssens, Neelke De Munck, and Johan Guns
3. KPIs for the IVF Laboratory
Alison Campbell
4. QC in the Clouds—Digitizing Quality Control
Giles Anthony Palmer
5. The Assisted Reproduction Technology Laboratory: Current Standards
Cecilia Sjöblom
6. Evaluation of Sperm
Chelsey A. Leisinger, Kaylen M. Silverberg, and Matthew D. VerMilyea
7. Sperm Preparation Techniques and Advanced Sperm Selection for Intracytoplasmic Sperm Injection
Sinan Ozkavukcu, George Hughes, and Christopher LR Barratt
8. Sperm Chromatin Assessment
Ashok Agarwal and Rakesh Sharma
9. Oocyte Retrieval and Selection
Laura Rienzi, Rosaria Gentile, Federica Innocenti, Danilo Cimadomo, Alberto Vaiarelli, and Filippo Maria Ubaldi
10. Preparation and Evaluation of Oocytes for Intracytoplasmic Sperm Injection
Irit Granot and Nava Dekel
11. Use of IVM in a Clinical Setting: What is its Role in ART?
Tuong M Ho and Lan N Vuong
12. Intracytoplasmic Sperm Injection: Technical Aspects
Sydney Souness, Philip Xie, Stephanie Cheung, Olena M. Kocur, Lily Ng, Zev Rosenwaks, and Gianpiero D. Palermo
13. Human Embryo Biopsy Procedures
Maurizio Poli, Ludovica Picchetta, and Antonio Capalbo
14. Analysis of Fertilization
Thomas Ebner
15. Culture Systems for the Human Embryo
David K. Gardner
16. Embryo Selection through the Analysis of Morphology and Physiology
Denny Sakkas and David K. Gardner
17. Evaluation of Embryo Quality: Time-Lapse Imaging to Assess Embryo Morphokinesis
Akhil Garg, María Ángeles Valera, and Marcos Meseguer
18. Artificial Intelligence (AI)
Daniella Gilboa
19. Artificial Intelligence (AI) in Gamete and Embryo Selection
Peter He, Neringa Karpaviciute, Cristina Hickman, and Nikica Zaninovic
20. Demystifying Vitrification
Debra A. Gook and Kelly Lewis
21. Vitrification of the Human Oocyte
Masashige Kuwayama
22. The Human Embryo: Vitrification
Zsolt Peter Nagy and Ching-Chien Chang
23. Managing an Oocyte Bank
Ana Cobo, Pilar Alamá, José María De Los Santos, María José De Los Santos, and José Remohí
24. Severe Male Factor Infertility: Genetic Consequences and Recommendations for Genetic Testing
Katrien Stouffs
25. Pre-Implantation Genetic Testing for Aneuploidy to Improve Clinical Outcomes
Jenna S. Hynes, Eric J. Forman, and Alan H. Handyside
26. Diagnosis of Endometrial Receptivity, Embryo–Endometrial Dialogue, and Endometrial Microbiome
Maria Ruiz-Alonso, Inmaculada Moreno, Felipe Vilella, and Carlos Simon
27. Artificial Gametes: Oocytes
Evelyn E Telfer and Yvonne L Odey
28. How Microfluidics and Microfabrication will Improve Diagnosis and Treatment in Human Art
Dale M. Goss, Steven A. Vasilescu, Majid E. Warkiani, Jeremy G. Thompson, and David K. Gardner
29. Genome Editing in Human Reproduction
Helen C O’Neill
30. Designing Disaster Plans for IVF Laboratories
Kimball O Pomeroy and Michael L Reed
31. Early Human Embryo Development Revealed by Static Imaging
Yanina D. Alvarez and Melanie D. White
Index
Biography
David K. Gardner AM, FAA, DPhil is a Professor in the School of BioSciences at the University of Melbourne, and is the Scientific Director of Melbourne IVF, Melbourne, Australia.
Ariel Weissman MD is a Senior Physician at the IVF Unit, Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, and a full Professor of Obstetrics and Gynecology at the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Colin M. Howles PhD, FRSM is based at Aries Consulting SARL, Geneva, Switzerland, and is an Honorary Fellow, University of Edinburgh, UK.
Zeev Shoham MD is a Professor at the Hebrew University, Jerusalem, Israel, a consultant in IVF, and co-founder of IVF-Worldwide.
