Textbook of Erectile Dysfunction  book cover
2nd Edition

Textbook of Erectile Dysfunction




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ISBN 9781841846460
Published December 22, 2008 by CRC Press
1176 Pages 250 B/W Illustrations

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Book Description

Erectile dysfunction (ED) affects 20-30 million American men, most of whom are over 50 years of age. In a UK-based study, 32% of British men had difficulty obtaining an erection, 20% with maintaining an erection. In recent years the physiology and pathophysiology of ED  have changed our understanding of what ED is from a purely psychological-based disorder to a multifactorial one, with neurological, endocrinological, psychological factors and the role of the vascular system. Recently identified risk factors include diabetes, cardiovascular disease, spinal cord injury, smoking, depression, atherosclerosis, hypertension, pelvic surgery and trauma, pharmacological medications, arthritis, peripheral vascular disease, substance abuse, endocrine abnormalities and peptic ulcer disease. Many ED patients have a combination of these risk factors, thus exacerbating ED further. The treatment of ED was revolutionized in 1998 with the introduction of sildenafil. Beside these oral treatments, newer injectable agents are being investigated as are topical preparations. However, not all patients are tolerant of oral agents, many patients still require penile reconstruction with penile implants, an option with low complications and morbidity. There are options for all patients and this excellent, updated text, edited by some of the world's leading authorities - Culley Carson, Roger Kirby and Irwin Goldstein - discusses them all.

Table of Contents

List of contributors
Preface
-Culley C Carson III, Roger S Kirby, Irwin Goldstein, and Michael G Wyllie
BASIC SCIENCE
The history of erectile dysfunction
Sachin Agrawal and William D Dunsmuir
The history of the International Society for Sexual Medicine Ronald W Lewis and Gorm Wagner
Epidemiology of erectile dysfunction Peter Boyle
Anatomy of erectile function William O Brant, Anthony J Bella, and Tom F Lue
Microscopic anatomy of erectile function Anthony J Bella, William O Brant, and Tom F Lue
Vascular physiology of erectile function Noel N Kim
Central nervous system control of sexual function in males and females Lesley Marson
Ejaculatory physiology Levent Gurkan, Austin DeRosa, and Wayne JG Hellstrom
Endocrinology of male sexual function Mario Maggi, Giovanni Corona, and Gianni Forti
Pathophysiology of erectile dysfunction: molecular basis Biljana Musicki and Arthur L Burnett
Neurotransmitters in the corpus cavernosum: nitric oxide and beyond Anthony J Bella, William O Brant, Gerald B Brock, and Tom F Lue
Receptor pharmacology related to erectile dysfunction Christian Gratzke, Tamer Abouschwareb, George J Christ, and Karl-Erik Andersson
Environmental erectile dysfunction Arthur L Burnett
Erectile dysfunction and treatment of carcinoma of the prostate Culley C Carson III

RISK FACTORS AND CLINICAL EVALUATION
Vascular risk factors and erectile dysfunction
Graham Jackson and Alethea Cooper
Mediterranean diet and erectile dysfunction Dario Giugliano, Myriam Ciotola, Francesco Giugliano, Massimo D’Armiento, and Katherine Esposito
Pharmacological risk factors for altered male sexual function Michael G Wyllie
Male sexual dysfunction and the prostate Michael G Wyllie
Basic assessment of the patient with erectile dysfunction Roger S Kirby and Michael G Kirby
The contemporary role of penile duplex scanning in sexual dysfunction Gerald Brock and Anthony Bella
Imaging in erectile dysfunction David Rickards
Neurophysiologic testing in erectile dysfunction Yoram Vardi and Ilan Gruenwald
Biopsy of the corpus cavernosum Eric Wespes
Endocrine evaluation of male sexual function Sanjay N Mediwala and Glenn R Cunningham
The biopsychosocial evaluation of erectile dysfunction Stanley E Althof and Rachel Needle
Erectile dysfunction: the couple contex William A Fisher, Alexandra McIntyre-Smith, and Michael Sand
Primary care evaluation and treatment of erectile dysfunction: American perspective Richard Sadovsky and Martin Miner

TREATMENT OF SEXUAL DYSFUNCTION
Phosphodiesterase type 5 inhibitors: molecular basis for pharmacological effects
Sharron H Francis and Jackie D Corbin
Phosphodiesterase type 5 inhibitors: non-erectile dysfunction cardiovascular effects Charalambos Vlachopoulos, Nikolaos Ioakeimidis, Konstantinos Rokkas, and Christodoulos Stefanadis
Sildenafil: first in the therapeutic class of phosphodiesterase type 5 inhibitors Culley C Carson III
Tadalafil: long-acting phosphodiesterase type 5 inhibitor Anthony J Bella and Gerald B Brock
Vardenafil: a biochemically potent phosphodiesterase type 5 inhibitor Sharron H Francis and Jackie D Corbin
The Princeton Guidelines for treatment Graham Jackson
Phosphodiesterase type 5 inhibitors: safety and adverse events Konstantinos Hatzimouratidis and Dimitrios Hatzichristou
Diagnosis and treatment of hypogonadism Mathew Oommen, Levent Gurkan, Allen D Seftel, and Wayne JG Hellstrom
Central nervous system agents for the treatment of erectile dysfunction Julita Mir and Ricardo Munárriz
Intracavernosal therapy for erectile dysfunction Carsten Maik Naumann, Moritz Franz Hamann, Sascha Kaufmann, Amr Al-Najar, Christof van der Horst, and Klaus-Peter Jünemann
Invicorp in erectile dysfunction Michael G Wyllie and W Wallace Dinsmore
Vacuum systems for erectile dysfunction Audrey C Rhee and Ronald W Lewis
Integrated sex therapy: a psychosocial–cultural perspective integrating behavioral, cognitive, and medical approaches Michael A Perelman
Gene therapy in erectile dysfunction: an update Tamer Aboushwareb, Christian Gratzke, Karl-Erik Andersson, and George J Christ
Stem and endothelial progenitor cells in erectile biology: future therapeutic applications and potential biomarker for erectile dysfunction Trinity J Bivalacqua, Travis D Strong, Hunter C Champion, and Arthur L Burnett
Mechanical, malleable, and soft semi-rigid penile implants for erectile dysfunction John J Mulcahy
Inflatable penile prostheses in erectile dysfunction (including penile shaft re-modeling in Peyronie’s disease) Daniel Yachia
Inflatable penile prostheses Culley C Carson III
Design, development, and use of questionnaires and surveys in the evaluation and management of sexual dysfunction: erectile dysfunction Glen W Barrisford and Michael P O’Leary
Assessment of male ejaculatory disorders Raymond C Rosen, Stanley E Althof, and Tara Symonds
Clinical trial design for erectile dysfunction Michael G Wyllie
Sexual function in congenital anomalies CRJ Woodhouse
Veno-occlusive impotence and erectile dysfunction: treatment and outcomes Aksam A Yassin and Farid Saad
Penile fracture: evaluation and management Osama KZ Shaeer and Kamal ZM Shaeer

SPECIAL PROBLEMS
Risks, complications, and outcomes of penile lengthening and augmentation procedures
Hunter Wessells and Jack W McAninch
Peyronie’s disease: evaluation and review of non-surgical therapy Frederick L Taylor and Laurence A Levine
Surgical treatment of Peyronie’s disease Culley C Carson III
Priapism Rajeev Kumar and Ajay Nehra
Phosphodiesterase type 5 inhibitor therapy for priapism Trinity J Bivalacqua, Biljana Musicki, Hunter C Champion, and Arthur L Burnett
Augmentation of phosphodiesterase type 5 inhibitor response with testosterone Antonio Aversa
Phosphodiesterase type 5 inhibitors for the treatment of women’s sexual function Salvatore Caruso, Agnello Carmela, and Lucia Di Mari
Erectile dysfunction and diabetes Suks Minhas, Ian Eardley, and Michael G Kirby
Chronic renal failure and sexual dysfunction Culley C Carson III and Aaron C Lentz
Evaluation of ejaculatory disorders Jason M Greenfield and Craig F Donatucci
Medical treatment of ejaculatory dysfunction Chris G McMahon
Topical agents for the treatment of premature ejaculation Michael G Wyllie
Potency-preserving surgery: radical prostatectomy and other pelvic surgery Paolo Gontero and Roger S Kirby
Rehabilitation of sexual function following prostatectomy Francesco Montorsi and Alberto Briganti
Sexual dysfunction and prostate cancer therapy John M Fitzpatrick, Roger S Kirby, Robert J Krane, Jan Adolfsson, Don WW Newling, and Irwin Goldstein
Gender reassignment surgery Michael Sohn and Klaus Exner
Index

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Reviews

'This textbook provides a comprehensive review of the major aspects of erectile dysfunction, with contributions from the acknowledged experts in this field ... The volume, which is presented in a clear, concise and extremely readable fashion, will be of particular interest to surgeons, physicians and health care workers interested in erectile dysfunction.' (British Journal of Surgery)