1176 Pages 250 B/W Illustrations
    by CRC Press

    Erectile dysfunction (ED) affects 20-30 million American men, most of whom are over 50 years of age. In a UK-based study, 32% of British men had difficulty obtaining an erection, 20% with maintaining an erection. In recent years the physiology and pathophysiology of ED  have changed our understanding of what ED is from a purely psychological-based disorder to a multifactorial one, with neurological, endocrinological, psychological factors and the role of the vascular system. Recently identified risk factors include diabetes, cardiovascular disease, spinal cord injury, smoking, depression, atherosclerosis, hypertension, pelvic surgery and trauma, pharmacological medications, arthritis, peripheral vascular disease, substance abuse, endocrine abnormalities and peptic ulcer disease. Many ED patients have a combination of these risk factors, thus exacerbating ED further. The treatment of ED was revolutionized in 1998 with the introduction of sildenafil. Beside these oral treatments, newer injectable agents are being investigated as are topical preparations. However, not all patients are tolerant of oral agents, many patients still require penile reconstruction with penile implants, an option with low complications and morbidity. There are options for all patients and this excellent, updated text, edited by some of the world's leading authorities - Culley Carson, Roger Kirby and Irwin Goldstein - discusses them all.

    List of contributors
    -Culley C Carson III, Roger S Kirby, Irwin Goldstein, and Michael G Wyllie
    The history of erectile dysfunction
    Sachin Agrawal and William D Dunsmuir
    The history of the International Society for Sexual Medicine Ronald W Lewis and Gorm Wagner
    Epidemiology of erectile dysfunction Peter Boyle
    Anatomy of erectile function William O Brant, Anthony J Bella, and Tom F Lue
    Microscopic anatomy of erectile function Anthony J Bella, William O Brant, and Tom F Lue
    Vascular physiology of erectile function Noel N Kim
    Central nervous system control of sexual function in males and females Lesley Marson
    Ejaculatory physiology Levent Gurkan, Austin DeRosa, and Wayne JG Hellstrom
    Endocrinology of male sexual function Mario Maggi, Giovanni Corona, and Gianni Forti
    Pathophysiology of erectile dysfunction: molecular basis Biljana Musicki and Arthur L Burnett
    Neurotransmitters in the corpus cavernosum: nitric oxide and beyond Anthony J Bella, William O Brant, Gerald B Brock, and Tom F Lue
    Receptor pharmacology related to erectile dysfunction Christian Gratzke, Tamer Abouschwareb, George J Christ, and Karl-Erik Andersson
    Environmental erectile dysfunction Arthur L Burnett
    Erectile dysfunction and treatment of carcinoma of the prostate Culley C Carson III

    Vascular risk factors and erectile dysfunction
    Graham Jackson and Alethea Cooper
    Mediterranean diet and erectile dysfunction Dario Giugliano, Myriam Ciotola, Francesco Giugliano, Massimo D’Armiento, and Katherine Esposito
    Pharmacological risk factors for altered male sexual function Michael G Wyllie
    Male sexual dysfunction and the prostate Michael G Wyllie
    Basic assessment of the patient with erectile dysfunction Roger S Kirby and Michael G Kirby
    The contemporary role of penile duplex scanning in sexual dysfunction Gerald Brock and Anthony Bella
    Imaging in erectile dysfunction David Rickards
    Neurophysiologic testing in erectile dysfunction Yoram Vardi and Ilan Gruenwald
    Biopsy of the corpus cavernosum Eric Wespes
    Endocrine evaluation of male sexual function Sanjay N Mediwala and Glenn R Cunningham
    The biopsychosocial evaluation of erectile dysfunction Stanley E Althof and Rachel Needle
    Erectile dysfunction: the couple contex William A Fisher, Alexandra McIntyre-Smith, and Michael Sand
    Primary care evaluation and treatment of erectile dysfunction: American perspective Richard Sadovsky and Martin Miner

    Phosphodiesterase type 5 inhibitors: molecular basis for pharmacological effects
    Sharron H Francis and Jackie D Corbin
    Phosphodiesterase type 5 inhibitors: non-erectile dysfunction cardiovascular effects Charalambos Vlachopoulos, Nikolaos Ioakeimidis, Konstantinos Rokkas, and Christodoulos Stefanadis
    Sildenafil: first in the therapeutic class of phosphodiesterase type 5 inhibitors Culley C Carson III
    Tadalafil: long-acting phosphodiesterase type 5 inhibitor Anthony J Bella and Gerald B Brock
    Vardenafil: a biochemically potent phosphodiesterase type 5 inhibitor Sharron H Francis and Jackie D Corbin
    The Princeton Guidelines for treatment Graham Jackson
    Phosphodiesterase type 5 inhibitors: safety and adverse events Konstantinos Hatzimouratidis and Dimitrios Hatzichristou
    Diagnosis and treatment of hypogonadism Mathew Oommen, Levent Gurkan, Allen D Seftel, and Wayne JG Hellstrom
    Central nervous system agents for the treatment of erectile dysfunction Julita Mir and Ricardo Munárriz
    Intracavernosal therapy for erectile dysfunction Carsten Maik Naumann, Moritz Franz Hamann, Sascha Kaufmann, Amr Al-Najar, Christof van der Horst, and Klaus-Peter Jünemann
    Invicorp in erectile dysfunction Michael G Wyllie and W Wallace Dinsmore
    Vacuum systems for erectile dysfunction Audrey C Rhee and Ronald W Lewis
    Integrated sex therapy: a psychosocial–cultural perspective integrating behavioral, cognitive, and medical approaches Michael A Perelman
    Gene therapy in erectile dysfunction: an update Tamer Aboushwareb, Christian Gratzke, Karl-Erik Andersson, and George J Christ
    Stem and endothelial progenitor cells in erectile biology: future therapeutic applications and potential biomarker for erectile dysfunction Trinity J Bivalacqua, Travis D Strong, Hunter C Champion, and Arthur L Burnett
    Mechanical, malleable, and soft semi-rigid penile implants for erectile dysfunction John J Mulcahy
    Inflatable penile prostheses in erectile dysfunction (including penile shaft re-modeling in Peyronie’s disease) Daniel Yachia
    Inflatable penile prostheses Culley C Carson III
    Design, development, and use of questionnaires and surveys in the evaluation and management of sexual dysfunction: erectile dysfunction Glen W Barrisford and Michael P O’Leary
    Assessment of male ejaculatory disorders Raymond C Rosen, Stanley E Althof, and Tara Symonds
    Clinical trial design for erectile dysfunction Michael G Wyllie
    Sexual function in congenital anomalies CRJ Woodhouse
    Veno-occlusive impotence and erectile dysfunction: treatment and outcomes Aksam A Yassin and Farid Saad
    Penile fracture: evaluation and management Osama KZ Shaeer and Kamal ZM Shaeer

    Risks, complications, and outcomes of penile lengthening and augmentation procedures
    Hunter Wessells and Jack W McAninch
    Peyronie’s disease: evaluation and review of non-surgical therapy Frederick L Taylor and Laurence A Levine
    Surgical treatment of Peyronie’s disease Culley C Carson III
    Priapism Rajeev Kumar and Ajay Nehra
    Phosphodiesterase type 5 inhibitor therapy for priapism Trinity J Bivalacqua, Biljana Musicki, Hunter C Champion, and Arthur L Burnett
    Augmentation of phosphodiesterase type 5 inhibitor response with testosterone Antonio Aversa
    Phosphodiesterase type 5 inhibitors for the treatment of women’s sexual function Salvatore Caruso, Agnello Carmela, and Lucia Di Mari
    Erectile dysfunction and diabetes Suks Minhas, Ian Eardley, and Michael G Kirby
    Chronic renal failure and sexual dysfunction Culley C Carson III and Aaron C Lentz
    Evaluation of ejaculatory disorders Jason M Greenfield and Craig F Donatucci
    Medical treatment of ejaculatory dysfunction Chris G McMahon
    Topical agents for the treatment of premature ejaculation Michael G Wyllie
    Potency-preserving surgery: radical prostatectomy and other pelvic surgery Paolo Gontero and Roger S Kirby
    Rehabilitation of sexual function following prostatectomy Francesco Montorsi and Alberto Briganti
    Sexual dysfunction and prostate cancer therapy John M Fitzpatrick, Roger S Kirby, Robert J Krane, Jan Adolfsson, Don WW Newling, and Irwin Goldstein
    Gender reassignment surgery Michael Sohn and Klaus Exner


    Culley C. Carson, Roger Kirby, Irwin Goldstein, Michael Wyllie

    'This textbook provides a comprehensive review of the major aspects of erectile dysfunction, with contributions from the acknowledged experts in this field ... The volume, which is presented in a clear, concise and extremely readable fashion, will be of particular interest to surgeons, physicians and health care workers interested in erectile dysfunction.' (British Journal of Surgery)