1st Edition
Textbook of Ion Channels Volume III Regulation, Physiology, and Diseases
Andrea L. Meredith
Chapter 2: Calmodulin Regulation of Ion Channels
Ivy Dick, David T. Yue, Manu Ben-Johny
Chapter 3: Mechanism of G-protein Regulation of Ion Channels
Kirin D. Gada, Rahul Mahajan, Diomedes E. Logothetis
Chapter 4: Regulation of Ion Channels by Membrane Lipids
Tibor Rohacs
Chapter 5: Ion Channels of the Heart
Donald M. Bers, Eleonora Grandi
Chapter 6: Ion Channels in Sperm and Eggs
Rachel E. Bainbridge, Anne E. Carlson
Chapter 7: Ion Channels in Immune Cells
Michael D. Cahalan, Thomas E. DeCoursey
Chapter 8: Ion Channels in Epilepsy
Jeffrey L. Noebels
Chapter 9: Ion Channels in Pain
Richard Dean, J. P. Johnson
Chapter 10: Cystic Fibrosis and the CFTR Anion Channels
Han-I Yeh, Tzyh-Chang Hwang
Chapter 11: CLC-Related Proteins in Diseases
Allan H. Bretag, Linlin Ma, Deanne H. Hryciw
Chapter 12: KATP Channels and the Regulation of Insulin Secretion
Mike Puljung
Biography
Jie Zheng, PhD, is a professor at the University of California Davis School of Medicine, where he has served as a faculty member in the Department of Physiology and Membrane Biology since 2004. Dr. Zheng earned a bachelor’s degree in physiology and biophysics (1988) and a master’s degree in biophysics (1991) at Peking University. He earned a PhD in physiology (1998) at Yale University, where he studied with Dr. Fredrick J. Sigworth on patch-clamp recording, single-channel analysis, and voltage-dependent activation mechanisms. He received his postdoctoral training at the Howard Hughes Medical Institute (HHMI) and the University of Washington during 1999–2003, working with Dr. William N. Zagotta on the cyclic nucleotide-gated channels activation mechanism and novel fluorescence techniques for ion channel research. Currently, Dr. Zheng’s research focuses on temperature-sensitive TRP channels.
Matthew C. Trudeau, PhD, is a professor in the Department of Physiology at the University of Maryland School of Medicine in Baltimore, Maryland. He earned a bachelor’s degree in biochemistry and molecular biology in 1992 and a PhD in physiology in 1998 while working with Gail Robertson, PhD, at the University of Wisconsin-Madison. His thesis work was on the properties of voltage-gated potassium channels in the human ether-aì-go-go related gene (hERG) family and the role of these channels in heart disease. Dr. Trudeau was a postdoctoral fellow with William Zagotta, PhD, at the University of Washington and the Howard Hughes Medical Institute (HHMI) in Seattle from 1998 to 2004, where he focused on the molecular physiology of cyclic nucleotide-gated ion channels, the mechanism of their modulation by calcium-calmodulin, and their role in an inherited form of vision loss. Currently, Dr. Trudeau’s work focuses on hERG potassium channels, their biophysical mechanisms, and their role in cardiac physiology and cardiac arrhythmias.
