This new edition focuses on a variety of techniques available for the analysis of drugs in biological fluids. Over 150 figures and tables help to describe the latest advances and give examples of their applications. Current chiral analysis methods as well as discussions on the impact of chirality are described. Practical aspects of bioanalytical work, including many examples of laboratory problems not often reported in the scientific literature, are examined in depth.
Why Analyze Drugs in Biological Fluids? Special Problems with Biological Fluids. Special Problems in Structures of Drugs. Spectroscopy and Fluorimetry. Planar Chromatography. Gas Chromatography. High-Performance Liquid Chromatography. Saturation Analysis: Radioimmunoassay and Other Ligand Assays. Miscellaneous Methods of Analysis. Development and Evaluation. Quality Control. Pitfalls and Practical Solutions. References. Index.