The Aspergilli : Genomics, Medical Aspects, Biotechnology, and Research Methods book cover
1st Edition

The Aspergilli
Genomics, Medical Aspects, Biotechnology, and Research Methods

ISBN 9780849390807
Published December 7, 2007 by CRC Press
576 Pages 88 B/W Illustrations

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Book Description

With high-quality genome sequences for the important and ubiquitous Aspergilli now available, increased opportunities arise for the further understanding of its gene function, interaction, expression, and evolution. The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods provides a comprehensive analysis of the research that reveals the main biological attributes of these species. The co-editors are a particularly proficient and prolific pair with long track records of scientific productivity.

The book sets the stage with a discussion of basic biology, examining the data on the structure of genomes and comparing the genetic map and annotation methodology. It includes a comparison of metabolic abilities among different Aspergillus spp. and other species, then covers areas such as comparative biology, pathogenic properties, and metabolic capabilities of the Aspergilli. The book reviews established techniques and new methodologies for the post-genomic era in Aspergillus spp. It comes with a CD containing color illustrations to supplement the text.

Filling the need for centralized information on a genus that has important economic impacts on agriculture, human health, industry, and pharmacology, the book presents a wide range of data, collected and arranged into one convenient resource. Written by a team of international experts, this is the first in-depth and exhaustive analysis of the genomics of the Aspergilli.

Table of Contents

Genomics of the Aspergilli

An Overview of the Genus Aspergillus, S.E. Baker and J.W. Bennett
A First Glance into the Genome Sequence of Aspergillus flavus, G.A. Payne, J. Yu, W.C. Nierman, M. Machida, D. Bhatnagar, T.E. Cleveland, and R.A. Dean
A Comparative View of the Genome of Aspergillus fumigatus, N.D. Fedorova, W.C. Nierman, G. Turner, V. Joardar, R. Maiti, M.J. Anderson, D.W. Denning, and J.R. Wortman
The Aspergillus nidulans Genome and a Comparative Analysis of Genome Evolution in Aspergillus, A. Rokas and J.E. Galagan
Aspergillus nidulans Linkage Map and Genome Sequence: Closing Gaps and Adding Telomeres, J. Clutterbuck and M. Farman
The Genome Sequence of Aspergillus oryzae, M. Machida

Basic Biology of the Aspergilli

Signal Transduction in Aspergilli, J.-H. Yu and C. d ’Enfert
Gene Regulation, M.X. Caddick and C. Dobson
Mitogen-Activated Protein Kinase Pathways in Aspergilli, G.S. May
Gluconeogenic Carbon Metabolism, M.J. Hynes
Amino Acid Supply of Aspergillus, O.W. Draht, S. Busch, K. Hofmann, S. Braus-Stromeyer, K. Helmstaedt, G.H. Goldman, and G.H. Braus
Endocytosis, J.C. Sánchez-Ferrero and M.A. Peñalva
RNA Silencing in the Aspergilli, T.M. Hammond and N.P. Keller
Hyphal Morphogenesis in Aspergillus nidulans, S.D. Harris
Cytoskeleton,Polarized Growth,and the Cell Cycle in Aspergillus nidulans, R. Fischer, N. Takeshita, and J. Doonan
The Nuclear Pore Complex and Transport in Aspergillus nidulans, E.A. Espeso and S.A. Osmani
Sexual Development in Aspergillus nidulans, D.-M. Han, K.-S. Chae, and K.-H Han
Aspergillus Transporters, G. Diallinas
Chromatin in the Genus Aspergillus, C. Scazzocchio and A. Ramón
Transposable Elements and Repeat-Induced Point Mutation in Aspergillus nidulans, Aspergillus fumigatus, and Aspergillus oryzae, A.J. Clutterbuck, V.V. Kapitonov, and J. Jurka

Medically Important Aspects of the Genus

Clinical Aspects of the Genus Aspergillus, W.J. Steinbach
Pathogenicity Determinants and Allergens, S. Krappmann
Mammalian Models of Aspergillosis, A.K. Zaas and W.J. Steinbach
The Emerging Role of Mini-Host Models in the Study of Aspergillosis, G. Chamilos and D.P. Kontoyiannis

Biotechnological Aspects of the Genus

Food Products Fermented by Aspergillus oryzae, K. Abe and K. Gomi
Aspergillus as a Cell Factory for Protein Production: Controlling Protease Activity in Fungal Production, M. Braaksma and P.J. Punt
Mycotoxin Production and Prevention of Aflatoxin Contamination in Food and Feed, J. Yu, G. Payne, B.C. Campbell, B. Guo, T.E. Cleveland, J.F. Robens, N.P. Keller, J.W. Bennett, and W.C. Nierman

Methods: Techniques and Resources

Microarrays in Aspergillus Species, A. Breakspear and M. Momany
Chemostats and Microarrays, M. Gent and K. Lanthaler
Advances in Gene Manipulations Using Aspergillus nidulans, S.A. Osmani, M. Hynes, and B.R. Oakley
Fluorescent Labels for Intracellular Structures and Organelles, B.R. Oakley and X. Xiang
Aspergillus at the Fungal Genetics Stock Center, K. McCluskey

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